추천 제품
생물학적 소스
rabbit
Quality Level
항체 형태
affinity purified immunoglobulin
항체 생산 유형
primary antibodies
클론
polyclonal
정제법
affinity chromatography
종 반응성
rat
제조업체/상표
Chemicon®
기술
ELISA: suitable
western blot: suitable
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
타겟 번역 후 변형
unmodified
유전자 정보
rat ... Slc4A1(24779)
특이성
Recognizes rat Anion Exchanger 1 (AE1). The immunogen shows no significant sequence homology with other AE or other proteins.
SPECIES REACTIVITIES: The immunogen sequence is 90% conserved in mouse, 75% in human and 70% in bovine. Reactivity with other species has not been confirmed.
SPECIES REACTIVITIES: The immunogen sequence is 90% conserved in mouse, 75% in human and 70% in bovine. Reactivity with other species has not been confirmed.
면역원
A 20 amino acid peptide sequence near the N-terminus of rat AE1 (Kudrycki et al. 1989; Kopito et al. 1985; Raida et al. 1989; Lux et al. 1989; Tanner et al. 1988).
애플리케이션
Anti-Anion Exchanger 1 Antibody detects level of Anion Exchanger 1 & has been published & validated for use in ELISA & WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Ion Channels & Transporters
Ion Channels & Transporters
Western blot: 1-10 μg/mL using ECL. AE1 has a molecular weight of approximately 90-100 kDa. It aggregates easily forming dimers and multimers. It may also be proteolytically processed to smaller fragments of 60, 40 and 20 kDa.
ELISA: 1-10 μg/mL using 1 μg/mL control peptide per well.
Optimal working dilutions must be determined by the end user.
ELISA: 1-10 μg/mL using 1 μg/mL control peptide per well.
Optimal working dilutions must be determined by the end user.
물리적 형태
Affinity purified immunoglobulin. Liquid in Liquid in PBS with 0.1% BSA.
저장 및 안정성
Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
SLC4A11 prevents osmotic imbalance leading to corneal endothelial dystrophy, deafness, and polyuria.
The Journal of biological chemistry, 285(19), 14467-14474 (2010-02-27)
Maintenance of ion concentration gradients is essential for the function of many organs, including the kidney, the cornea, and the inner ear. Ion concentrations and fluid content in the cornea are regulated by endothelial cells that separate the collagenous avascular
Human molecular genetics, 21(5), 1025-1036 (2011-11-16)
The human SLC4A5 gene has been identified as a hypertension susceptibility gene based on the association of single nucleotide polymorphisms with blood pressure (BP) levels and hypertension status. The biochemical basis of this association is unknown particularly since no single
Human molecular genetics, 17(11), 1505-1516 (2008-02-12)
Polycystic kidney disease (ADPKD) results from failure of the kidney to properly maintain three-dimensional structure after loss of either polycystin-1 or -2. Mice with kidney selective inactivation of Pkd1 during embryogenesis develop profound renal cystic disease and die from renal
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