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Merck
모든 사진(3)

Key Documents

AB2283

Sigma-Aldrich

Anti-Tbr2 Antibody

from rabbit, purified by affinity chromatography

동의어(들):

eomesodermin (Xenopus laevis) homolog, eomesodermin homolog (Xenopus laevis), t box, brain, 2

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

정제법

affinity chromatography

종 반응성

human, mouse

기술

immunohistochemistry: suitable

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... EOMES(8320)
mouse ... Eomes(13813)

일반 설명

Tbr2 (a T-domain transcription factor) is a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Trb2 has been shown to play a role in the development of the neocortex and functions in the differentiation pathway of radial glia to postmitotic projection neuron.

특이성

This antibody recognizes Tbr2.

면역원

Epitope: Internal Domain
KLH-conjugated linear peptide corresponding to mouse Tbr2.

애플리케이션

Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience
This Anti-Tbr2 Antibody is validated for use in IH for the detection of Tbr2.

품질

Evaluated by Immunohistochemistry of human brain tissue.

Immunohistochemistry Analysis: A 1:300 dilution of Anti-Tbr2 antibody from a previous lot detected Tbr2 in mouse and human brain tissue.

물리적 형태

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
Human Brain Tissue

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

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Shi, Yichen, et al.
Science Translational Medicine, 4, 124ra29-124ra29 (2012)
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The Journal of neuroscience : the official journal of the Society for Neuroscience, 30(32), 10752-10762 (2010-08-13)
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Joanna Yeung et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 36(35), 9057-9069 (2016-09-02)
Pax6 is a prominent gene in brain development. The deletion of Pax6 results in devastated development of eye, olfactory bulb, and cortex. However, it has been reported that the Pax6-null Sey cerebellum only has minor defects involving granule cells despite

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