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Merck
모든 사진(1)

Key Documents

AB16661

Sigma-Aldrich

Anti-PARP Poly ADP-ribose Polymerase-1 Antibody

serum, Chemicon®

동의어(들):

Poly [ADP-ribose] polymerase 1, PARP-1, NAD(+) ADP-ribosyltransferase 1, ADPRT 1, Poly[ADP-ribose] synthase 1, ARTD1

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

항체 형태

serum

항체 생산 유형

primary antibodies

클론

polyclonal

종 반응성

rat, human, bovine, mouse

제조업체/상표

Chemicon®

기술

ELISA: suitable
western blot: suitable

NCBI 수납 번호

UniProt 수납 번호

배송 상태

dry ice

타겟 번역 후 변형

unmodified

유전자 정보

bovine ... Parp1(286764)
human ... PARP1(142)
mouse ... Parp1(11545)
rat ... Parp1(25591)

특이성

Recognizes 116 kDa PARP-1 and the 85 kDa apoptosis-related cleavage fragment.

면역원

Synthetic peptide based on the sequence from the C-terminal portion of the bovine PARP automodification domain (amino acids 509-524) conjugated to a carrier.

애플리케이션

Research Category
Apoptosis & Cancer

Metabolism
Research Sub Category
Apoptosis - Additional

Enzymes & Biochemistry
This Anti-PARP Poly ADP-ribose Polymerase-1 Antibody is validated for use in ELISA, WB for the detection of PARP Poly ADP-ribose Polymerase-1.
Western blot: 1:500 using alkaline phosphatase.

ELISA

Optimal working dilutions must be determined by end user.

결합

Replaces: 04-575; 04-576

물리적 형태

Antiserum containing 0.05% sodium azide. Liquid containing 0.05% sodium azide.

저장 및 안정성

Maintain frozen at -20°C in undiluted aliquots for up to 12 months.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1


시험 성적서(COA)

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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Y A Lazebnik et al.
Nature, 371(6495), 346-347 (1994-09-22)
Recent studies suggest that proteases of the interleukin 1-beta-converting enzyme (ICE)/ced-3 family are involved in initiating the active phase of apoptosis. Here we identify a novel protease resembling ICE (prICE) that is active in a cell-free system that reproduces the
D Lamarre et al.
Biochimica et biophysica acta, 950(2), 147-160 (1988-07-13)
Poly(ADP ribose) polymerase (EC 2.4.2.30) was studied using monoclonal antibodies for three different epitopes on the enzyme. The epitopes were mapped in relation to the functional domains of the protein and the inhibitory properties of the antibodies. The intranuclear and
Lauren K Jillson et al.
Molecular cancer research : MCR, 19(7), 1123-1136 (2021-04-14)
Prostate cancer genomic subtypes that stratify aggressive disease and inform treatment decisions at the primary stage are currently limited. Previously, we functionally validated an aggressive subtype present in 15% of prostate cancer characterized by dual deletion of MAP3K7 and CHD1.
MiR-129-5p is required for histone deacetylase inhibitor-induced cell death in thyroid cancer cells.
Brest, P; Lassalle, S; Hofman, V; Bordone, O; Gavric Tanga, V; Bonnetaud, C; Moreilhon et al.
Endocrine-Related Cancer null
Hypermethylated in cancer 1 (HIC1), a tumor suppressor gene epigenetically deregulated in hyperparathyroid tumors by histone H3 lysine modification.
Svedlund, J; Koskinen Edblom, S; Marquez, VE; ?kerstrom, G; Bjorklund, P; Westin, G
The Journal of clinical endocrinology and metabolism null

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