AB15558

Anti-Somatostatin Receptor Type 2 Antibody

• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.43

속성

• 항체 형태: purified antibody
• Quality Level: 100
• 클론: polyclonal
• 정제법: (ImmunoAffinity Purified)
• 종 반응성: rat, mouse, rabbit
• 기술: immunohistochemistry: suitable; western blot: suitable
• UniProt 수납 번호: Q92796

설명

일반 설명

FUNCTION: SwissProt: Q92796 # Required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling.
SIZE: 817 amino acids; 90344 Da
SUBUNIT: Interacts through its PDZ domains with GRIN2B and SYNGAP1. Interacts through its guanylate kinase-like domain with DLGAP1, DLGAP2, DLGAP3 and DLGAP4 (By similarity). Interacts through its PDZ domains with APC. Interacts through its first two PDZ domains with ERBB4. Interacts through its third PDZ domain with NLGN1, and probably with NLGN2 and NLGN3.
DISEASE: SwissProt: Q92796 # Defects in DLG3 are the cause of non-syndromic mental retardation X-linked type 90 (MRX90) [MIM:300189]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non- syndromic mental retardation patients do not manifest other clinical signs.
SIMILARITY: SwissProt: Q92796 ## Belongs to the MAGUK family. & Contains 1 guanylate kinase-like domain. & Contains 3 PDZ (DHR) domains. & Contains 1 SH3 domain.

Purified peptide from the N-terminus of rat Somatostatin Receptor Type 2 (Accession number P30680).

특이성

Recognizes Somatostatin Receptor Type 2 (SSTR2).

애플리케이션

Western blot: 1:200-1:500 using ECL on rat brain and pancreas lysate.
Dilutions should be made using a carrier protein such as BSA (1-3%).

Optimal working dilutions must be determined by the end user.

물리적 형태

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, and 0.05% sodium azide as a preservative. Reconstitute with 200 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min).

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, and 0.05% sodium azide as a preservative. Reconstitute with 50 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min).

저장 및 안정성

Maintain lyophilized material at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

기타 정보

Included free of charge with the antibody is 40 µg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 µL of sterile deionized water. For negative control, preincubate 1 µg of peptide with 1 µg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.

The immunogen sequence is 12 of 15 amino acids identical in human and porcine.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids