AB1254
Anti-Cytochrome P450 Enzyme CYP3A4 Antibody
serum, Chemicon®
동의어(들):
Anti-Anti-CP33, Anti-Anti-CP34, Anti-Anti-CYP3A, Anti-Anti-CYP3A3, Anti-Anti-CYPIIIA3, Anti-Anti-CYPIIIA4, Anti-Anti-HLP, Anti-Anti-NF-25, Anti-Anti-P450C3, Anti-Anti-P450PCN1, Anti-Anti-VDDR3
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모든 사진(1)
About This Item
UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41
추천 제품
생물학적 소스
rabbit
Quality Level
항체 형태
serum
항체 생산 유형
primary antibodies
클론
polyclonal
종 반응성
human, pig
종 반응성(상동성에 의해 예측)
mammals, rat
제조업체/상표
Chemicon®
기술
immunohistochemistry: suitable
western blot: suitable
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... CYP3A4(1576)
특이성
The rabbit polyclonal serum detects CYP3A4 in humans and rats; by sequence homology of the immunogen used, cross reactivity to CYP3A7, 3A6v4;3A2v1, 3A8, 3A9 may be expected but is untested at this time.
면역원
A synthetic peptide containing the C-terminal sequence of TVSGA from human CYP3A4. The peptide was coupled to KLH.
애플리케이션
Anti-Cytochrome P450 Enzyme CYP3A4 Antibody detects level of Cytochrome P450 Enzyme CYP3A4 & has been published & validated for use in IH & WB.
Research Category
Metabolism
Metabolism
Research Sub Category
Enzymes & Biochemistry
Enzymes & Biochemistry
Western blot: 1:1000-1:2000: Using microsomal membrane fractions, detects a band at ~54kDa; other bands may be present as well. Antibody has been successfully used to detect CYP3A4 on LICOR fluorescent westerns as well.
Immunohistochemistry: 10% formalin fixed, paraffin embedded tissues 1:200-1:400, microwave-citric acid antigen recovery is suggested.
Optimal working dilutions must be determined by end user.
Immunohistochemistry: 10% formalin fixed, paraffin embedded tissues 1:200-1:400, microwave-citric acid antigen recovery is suggested.
Optimal working dilutions must be determined by end user.
표적 설명
57 kDa
물리적 형태
Rabbit antiSerum. Liquid containing no preservative.
Unpurified
저장 및 안정성
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
분석 메모
Control
Liver tissue
Liver tissue
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Pattern of P450 expression at the human blood-brain barrier: roles of epileptic condition and laminar flow.
Ghosh, C; Gonzalez-Martinez, J; Hossain, M; Cucullo, L; Fazio, V; Janigro, D; Marchi, N
Epilepsia null
The application of 3D micropatterning of agarose substrate for cell culture and in situ comet assays.
Emilie Mercey,Patricia Obeid,Denise Glaise,Maria-Luisa Calvo-Mu?oz et al.
Biomaterials null
K Pernelle et al.
Toxicology and applied pharmacology, 254(3), 256-266 (2011-05-17)
In this study, our goal was to develop an efficient in situ test adapted to screen hepatotoxicity of various chemicals, a process which remains challenging during the early phase of drug development. The test was based on functional human hepatocytes
Cellular localization and functional significance of CYP3A4 in the human epileptic brain.
Ghosh, C; Marchi, N; Desai, NK; Puvenna, V; Hossain, M; Gonzalez-Martinez, J; Alexopoulos et al.
Epilepsia null
Manuel Vlach et al.
Cells, 11(23) (2022-12-12)
The goal of this study was to establish a procedure for gene delivery mediated by cationic liposomes in quiescent differentiated HepaRG™ human hepatoma cells. We first identified several cationic lipids promoting efficient gene transfer with low toxicity in actively dividing
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