AB10140

Anti-Drebrin A/E Antibody

from rabbit, purified by affinity chromatography

• 동의어(들): Developmentally-regulated brain protein, drebrin 1, drebrin E, drebrin E2
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: rat, human, mouse
• 기술: immunocytochemistry: suitable; western blot: suitable
• NCBI 수납 번호: NM_004395.3
• UniProt 수납 번호: Q07266
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... DBN1(1627)

설명

일반 설명

The developmentally-regulated neuron-specific protein, Drebrin A, is expressed first at the time of outgrowth and maturation of dendrites, and is localized within dendrites of the adult brain. Drebrin E+A- signals have been observed in the cell bodies of migrating neuroblasts in the core region; however, only fibrous and punctate drebrin E+A- signals were observed in postmigratory neuroblasts at the outer layers. Studies have demonstrated that the disappearance of drebrin E+A- signals from the cell body coincides with the cessation of neuronal migration. The disappearance of drebrin E from the cell body may be a molecular switch for the cessation of migration in newly generated neuroblast

특이성

Cat. # AB10140 detects the internal domain of Drebrin A/E.

May react with human based on sequence homology. Reactivity with other species has not been determined.

면역원

Epitope: Internal Domain

KLH conjugated synthetic linear peptide.

애플리케이션

Detect Drebrin A/E using this Anti-Drebrin A/E Antibody validated for use in WB & IC.

Immunocytochemistry: Proven to react with Drebrin A/E in 16 DIV rat cortical neurons. Photo courtesy of Dr. Gang Lui, Drexel University.

Research Category
Neuroscience

Research Sub Category
Synapse & Synaptic Biology

품질

Western Blot:
A 1:5,000 dilution of this antibody was used to detect embryonic rat brain (day 16) tissue lysate.

표적 설명

~77 kDa

물리적 형태

Antigen Affinity Purified

Purified rabbit polyclonal antibody in PBS with 0.05% NaN3.

저장 및 안정성

Stable for 1 year at 2-8ºC from date of receipt.

분석 메모

Control
Embryonic rat brain (day 16) tissue lysate.

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable