8.52245

Fmoc-D-Thr(PO(OBzl)OH)-OH

Novabiochem^®

• 동의어(들): Fmoc-D-Thr(PO(OBzl)OH)-OH, N-α-Fmoc-O-benzyl-D-phosphothreonine
• 실험식(Hill 표기법): C₂₆H₂₆NO₈P
• CAS Number: 937171-63-6
• Molecular Weight: 511.46
• UNSPSC 코드: 12352209

속성

• 제품 라인: Novabiochem^®
• 분석: ≥90.0% (acidimetric); ≥95.0% (HPLC); ≥97% (TLC)
• 형태: powder
• 반응 적합성: reaction type: Fmoc solid-phase peptide synthesis
• 제조업체/상표: Novabiochem^®
• 응용 분야: peptide synthesis
• 작용기: Fmoc
• 저장 온도: 15-25°C

설명

일반 설명

An excellent building block for the preparation of D-phosphothreonine-containing peptides by Fmoc SPPS. This derivative can be introduced using standard activation methods, such as PyBOP^® and TBTU. The monoprotected phosphoserine residue once incorporated is stable to piperidine. Using this reagent, even peptides containing multiple phosphorylation sites can be prepared efficiently by standard Fmoc SPPS methods.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Fmoc SPPS of Peptides containing Post-Translational Modifications

결합

Replaces: 04-13-1079

분석 메모

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in DMF): +3.5 - +6.5 °
Purity (TLC(CMA1)): ≥ 97 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 90.0 %
Water (K. F.): ≤ 2.00 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

법적 정보

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

PyBOP is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable