8.52136

Fmoc-Ser(Ac3AcNH-α-Gal)-OH

Novabiochem^®

• 동의어(들): Fmoc-Ser(Ac3AcNH-α-Gal)-OH, N-α-Fmoc-O-(2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-α-D-galactopyranosyl)-L-serine
• 실험식(Hill 표기법): C₃₂H₃₆N₂O₁₃
• CAS Number: 120173-57-1
• Molecular Weight: 656.63
• MDL number: MFCD00171375
• UNSPSC 코드: 12352209
• NACRES: NA.22

속성

• Quality Level: 200
• 제품 라인: Novabiochem^®
• 분석: ≥95% (TLC); ≥95.0% (HPLC)
• 양식: powder
• 반응 적합성: reaction type: Fmoc solid-phase peptide synthesis
• 제조업체/상표: Novabiochem^®
• 응용 분야: peptide synthesis
• 작용기: Fmoc
• 저장 온도: 15-25°C
• SMILES string: N([C@H]1[C@H](O[C@@H]([C@@H]([C@@H]1OC(=O)C)OC(=O)C)COC(=O)C)OC[C@H](NC(=O)OCC2c3c(cccc3)c4c2cccc4)C(=O)O)C(=O)C
• InChI: 1S/C32H36N2O13/c1-16(35)33-27-29(46-19(4)38)28(45-18(3)37)26(15-42-17(2)36)47-31(27)43-14-25(30(39)40)34-32(41)44-13-24-22-11-7-5-9-20(22)21-10-6-8-12-23(21)24/h5-12,24-29,31H,13-15H2,1-4H3,(H,33,35)(H,34,41)(H,39,40)/t25-,26+,27+,28-,29+,31-/m0/s1
• InChI key: ORICVOOXZDVFIP-VOZJJELXSA-N

설명

일반 설명

The O-glycosidic linkage and the O-acetyl protection in this building block is stable to both piperidine and TFA ^[1], making it completely compatible with standard protocols in Fmoc solid phase peptide synthesis. Removal of the acetyl protecting groups is best carried out by treatment of the peptidyl resin with methanolic ammonia prior to cleavage.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Fmoc SPPS of Peptides containing Post-Translational Modifications


Literature references

^[1] J. Kihlberg in ′Fmoc solid phase peptide synthesis: a practical approach′, W.C. Chan & P.D. White (Eds.), Oxford University Press, Oxford, 2000, pp. 195.

결합

Replaces: 04-12-8103

분석 메모

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(CMA2)): ≥ 95 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Identity (NMR, 1H): passes test
Identity (NMR): passes test
NMR-spectrum: passes test

To see the solvent systems used for TLC of Novabiochem^® products please click here.

법적 정보

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable