539149

Proteasome Substrate VI, Fluorogenic

A fluorogenic substrate probe useful for assaying trypsin-like activity of proteasome.

• 동의어(들): Proteasome Substrate VI, Fluorogenic, Z-ARR-AMC, 2HCl
• 실험식(Hill 표기법): C₃₃H₄₄N₁₀O₇ · 2HCl
• CAS Number: 90468-18-1
• Molecular Weight: 765.69
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 형태: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; protect from light
• 색상: white to off-white
• solubility: DMSO: 200 mg/mL; 80% acetic acid: 50 mg/mL; methanol: soluble
• 형광: λ_ex ~380 nm; λ_em ~460 nm
• 배송 상태: ambient
• 저장 온도: −20°C

설명

일반 설명

A fluorogenic substrate for assaying trypsin-like activity of proteasome. Also serves as a substrate for cathepsin B. Excitation max: 360-380 nm; emission max.: 430-460 nm.

A fluorogenic substrate probe useful for assaying trypsin-like activity of proteasome. Also reported to be a specific substrate for cathepsin B.

생화학적/생리학적 작용

Cell permeable: no

Primary Target
Proteasome

Product does not compete with ATP.

Reversible: no

포장

Packaged under inert gas

경고

Toxicity: Standard Handling (A)

서열

Z-Ala-Arg-Arg-AMC

물리적 형태

Supplied as hydrochloride salt.

재구성

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 3 months at -20°C

기타 정보

Geier, E., et al. 1999. Science283, 978.
Dick, T.P., et al. 1998. J. Biol. Chem. 273, 25637.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable