5.30748

SRT1720 HCl

InSolution, ≥98%, 25 mM in DMSO

• 동의어(들): InSolution SRT1720, HCl, N-(2-(3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-quinolinecarboxamide, 4HCl;, Histone Acetyltransferase Inhibitor XI, p300/CBP Inhibitor IX, SRT1720, HCl InSolution, HAT Inhibitor XI, SIRT3 Inhibitor II, Sirtuin-3 In
• 실험식(Hill 표기법): C₂₅H₂₃N₇OS · xHCl
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 형태: liquid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; avoid repeated freeze/thaw cycles; desiccated (hygroscopic); protect from light
• 저장 온도: −70°C
• InChI: 1S/C25H23N7OS.ClH/c33-24(22-13-27-20-7-3-4-8-21(20)28-22)29-19-6-2-1-5-18(19)23-15-32-17(16-34-25(32)30-23)14-31-11-9-26-10-12-31;/h1-8,13,15-16,26H,9-12,14H2,(H,29,33);1H
• InChI key: DTGRRMPPXCRRIM-UHFFFAOYSA-N

설명

일반 설명

An enhanced aqueous soluble version of SRT1720 (Cat. No. 567860).

An enhanced aqueous soluble version of SRT1720 (Cat. No. 567860).

Please note that the molecular weight for this compound is batch-specific due to variable water content.

생화학적/생리학적 작용

Cell permeable: yes

Primary Target
SIRT3

Reversible: yes

Secondary Target
p300 HAT

포장

Packaged under inert gas

경고

Toxicity: Standard Handling (A)

물리적 형태

A 25 mM (10 mg/650 µl) sterile-filtered solution of SRT1720, HCl (Cat. No. 567860) in DMSO.

재구성

Following initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.

기타 정보

Baur, J.A., et al. 2012. Nat. Rev. Drug Discov.11, 443.
Minor, R.K., et al. 2011. Sci. Rep.1, 70.

Huber, J.L., et al. 2010. Future Med. Chem.2, 1751.
Pacholec, M., et al. 2010. J. Biol. Chem.285, 8340.
Jin, L., et al. 2009. Protein Sci.18, 514.
Feige, J.N., et al. 2008. Cell Metab.8, 347.
Milne, J.C., et al. 2007. Nature450, 712.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): 188.6 °F
• Flash Point (°C): 87 °C