530006

Prion Protein, His•Tag^®, Human, Recombinant, E. coli

• 동의어(들): rhPrP ^c, rhPrP^c
• UNSPSC 코드: 12352202
• NACRES: NA.32

속성

• 분석: ≥95% (SDS-PAGE)
• Quality Level: 100
• 형태: liquid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; avoid repeated freeze/thaw cycles
• 배송 상태: wet ice
• 저장 온도: −20°C

설명

일반 설명

Recombinant, human prion protein (amino acids 23-231) fused to a His•Tag sequence and expressed in E. coli. Prion diseases or transmissible spongiform encephalopathies are neurodegenerative diseases that affect both humans and animals. All prion diseases share the same molecular pathogenic mechanism that involves conversion of normal cellular prion protein (PrPc) into a form that is insoluble in non-ionic detergent and partially resistant to proteases (PrPsc). Useful as an antigen standard in immunochemical detection of Creutzfeldt-Jakob Disease (CJD).

Recombinant, human prion protein (amino acids 23-231) fused to a His•Tag sequence and expressed in E. coli. Useful as an antigen standard in immunochemical detection of Creutzfeldt-Jakob Disease (CJD).

경고

Toxicity: Standard Handling (A)

물리적 형태

In 10 mM sodium acetate, pH 4.0.

재구성

Following initial thaw, aliquot and freeze (-20°C).

기타 정보

Calzolai, L., and Zahn, R. 2003. J. Biol. Chem.278, 35592.
Prusiner, S.B. 1998. Proc. Natl. Acad. Sci. USA95, 13363.
Swietnicki, W., et al. 1997. J. Biol. Chem.272, 27517.
Pan, K.M., et al. 1993. Proc. Natl. Acad. Sci. USA90, 10962.
Basler, K., et al. 1986. Cell46, 417.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable