495417-M

N-Oleoyl Ethanolamine

A potent inhibitor of the ceramidase found in human kidney and cerebellum.

• 동의어(들): N-Oleoyl Ethanolamine, N-2-Hydroxyethyl-9(Z)-octadecenamide, AC Inhibitor I, Acid Ceramidase Inhibitor I, OEA
• 실험식(Hill 표기법): C₂₀H₃₉NO₂
• CAS Number: 111-58-0
• Molecular Weight: 325.53
• MDL number: MFCD00045972
• UNSPSC 코드: 12352211

속성

• Quality Level: 100
• 분석: ≥98% (TLC)
• 형태: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• 색상: white
• solubility: chloroform: 5 mg/mL; ethanol: 5 mg/mL; methanol: 5 mg/mL
• 저장 온도: −20°C
• InChI: 1S/C20H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h9-10,22H,2-8,11-19H2,1H3,(H,21,23)/b10-9-
• InChI key: BOWVQLFMWHZBEF-KTKRTIGZSA-N

설명

일반 설명

A potent inhibitor of the ceramidase found in human kidney and cerebellum. A specific inhibitor of acid ceramidase (IC₅₀ ~ 500 µM).

A potent inhibitor of the ceramidase found in human kidney and cerebellum. Blocks the conversion of ceramide to sphingosine. A specific inhibitor of acid ceramidase (IC₅₀ ~ 500 µM).

생화학적/생리학적 작용

Primary Target
Acid ceramidase

Target IC₅₀: ~ 500 µM against acid ceramidase

경고

Toxicity: Standard Handling (A)

기타 정보

Pahan, K., et al. 1998. J. Biol. Chem. 273, 2591.
Ping, S.E., and Barrett, G.L. 1998. J. Neurosci. Res. 54, 206.
Sugita, M., et al. 1975. Biochim. Biophys. Acta398, 125.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable