428026

Latrunculin A

from Latrunculia magnifica, ≥85% (HPLC), liquid, actin polymerization inhibitor, Calbiochem

• 동의어(들): InSolution Latrunculin A, Latrunculia magnifica
• 실험식(Hill 표기법): C₂₂H₃₁NO₅S
• Molecular Weight: 421.55
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• 제품명: Latrunculin A, Latrunculia magnifica, InSolution, ≥85%, 1 mM in DMSO, marine toxin that disrupts microfilament organization in cultured cells
• Quality Level: 100
• 분석: ≥85% (HPLC)
• 양식: liquid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; desiccated (hygroscopic); protect from light
• 배송 상태: wet ice
• 저장 온도: −20°C

설명

일반 설명

A cell-permeable marine toxin from the Red Sea sponge Latrunculia magnifica that disrupts microfilament organization in cultured cells by the formation of a 1:1 complex with monomeric G-actin (K_d = 200 nM). Also a potent inhibitor of microfilament-mediated processes in sperm, eggs, and embryos.

생화학적/생리학적 작용

Cell permeable: yes

Primary Target
Inhibitor of microfilament-mediated processes in sperm, eggs, and embryos

Product does not compete with ATP.

Reversible: no

포장

Packaged under inert gas

경고

Toxicity: Harmful (C)

물리적 형태

A 1 mM (50 µg/119 µl) solution of Latrunculin A, Latrunculia magnifica Cat. No. 428021 in DMSO.

재구성

Following initial use, aliquot and freeze (-20°C).

기타 정보

Ayscough, K.R., et al. 1997. J. Cell Biol.137, 399.
Spector, I., et al. 1989. Cell Motil. Cytoskeleton13, 127.
Coue, M., et al. 1987. FEBS Lett.213, 316.
Schatten, G., et al. 1986. Exp. Cell Res.166, 191.
Spector, I., et al. 1983. Science219, 493.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): 188.6 °F - (refers to pure substance)
• Flash Point (°C): 87 °C - (refers to pure substance)