362339

Glyco-SNAP-2

A water-soluble nitric oxide (NO) donor that exhibits greater stability (t1/2 = 27 hours) than that of SNAP.

• 동의어(들): Glyco-SNAP-2, N-(2-Deoxy-α,β-D-glucopyranose-2-)-N²-acetyl-S-nitroso-D,L-penicillaminamide
• 실험식(Hill 표기법): C₁₃H₂₃N₃O₈S
• CAS Number: 188849-82-3
• Molecular Weight: 381.40
• UNSPSC 코드: 12352200
• PubChem Substance ID: 3413551
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥95% (HPLC)
• 형태: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; protect from light
• 색상: green
• solubility: aqueous buffer: >100 mg/mL; methanol: soluble; water: soluble
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: CC(=O)NC(C(=O)NC1C(C(C(OC1O)CO)O)O)C(C)(C)SN=O

설명

일반 설명

A nitric oxide donor that exhibits greater stability than SNAP in aqueous medium, in both the presence and absence of EDTA. The half life of Glyco-SNAP-2 in aqueous medium is 27.4 h at room temperature, in the absence of EDTA, compared to 10.3 h for SNAP. The compound consists of a S-nitroso-N-acetylpencilamine moiety, which acts as a NO-donor, and a sugar fragment, which provides the desired hydrophobicity.

A water-soluble nitric oxide (NO) donor that exhibits greater stability (t_½ = 27 hours) than that of SNAP. Exhibits properties similar to those of Glyco-SNAP-1 (Cat. No. 362338).

생화학적/생리학적 작용

Cell permeable: no

Primary Target
Water-soluble nitric oxide (NO) donor

Product does not compete with ATP.

Reversible: no

경고

Toxicity: Standard Handling (A)

재구성

Unstable in solution; reconstitute just prior to use.

기타 정보

Hou, Y., et al. 1999. Methods Enzymol. 301, 242.
Ramirez, J., et al. 1996. Bioorg. Med. Chem. Lett.6, 2575.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable