362000
N-Glycolylneuraminic Acid
Formed by the action of CMP-Neu5Ac hydroxylase. Humans are devoid of this compound due to a mutation in the human CMP-Neu5Ac hydroxylase gene that occurred after the Homo-Pan divergence.
동의어(들):
N-Glycolylneuraminic Acid, NeuGc, Neu5Gc
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C11H19NO10
CAS Number:
Molecular Weight:
325.27
MDL number:
UNSPSC 코드:
12352201
NACRES:
NA.79
추천 제품
Quality Level
분석
≥98% (HPLC)
양식
solid
제조업체/상표
Calbiochem®
저장 조건
OK to freeze
색상
off-white
solubility
water: 10 mg/mL
배송 상태
ambient
저장 온도
−20°C
InChI
1S/C10H17NO10/c12-1-3(14)6(16)7(17)5(11-4(15)2-13)8(18)9(19)10(20)21/h3,5-8,12-14,16-18H,1-2H2,(H,11,15)(H,20,21)/t3-,5+,6-,7-,8-/m1/s1
InChI key
YIICUBSXBNCXHW-BOSCHMPASA-N
일반 설명
Formed by the action of CMP-Neu5Ac hydroxylase. A major component in great ape tissues except brain; however, it is absent in man due to a mutation in the human CMP-Neu5Ac hydroxylase gene that is reported to have occurred after the Homo-Pan divergence.
Formed by the action of CMP-Neu5Ac hydroxylase. Humans are devoid of this compound due to a mutation in the human CMP-Neu5Ac hydroxylase gene that occurred after the Homo-Pan divergence.
경고
Toxicity: Standard Handling (A)
기타 정보
Chou, H.H., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 11751.
Malykh, Y.N., et al. 1998. Glycoconj. J. 15, 885.
Malykh, Y.N., et al. 1998. Glycoconj. J. 15, 885.
법적 정보
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
이미 열람한 고객
H H Chou et al.
Proceedings of the National Academy of Sciences of the United States of America, 95(20), 11751-11756 (1998-09-30)
Sialic acids are important cell-surface molecules of animals in the deuterostome lineage. Although humans do not express easily detectable amounts of N-glycolylneuraminic acid (Neu5Gc, a hydroxylated form of the common sialic acid N-acetylneuraminic acid, Neu5Ac), it is a major component
Y N Malykh et al.
Glycoconjugate journal, 15(9), 885-893 (1999-03-03)
The biosynthesis of the sialic acid N-glycolylneuraminic acid (Neu5Gc) occurs by the action of cytidine monophosphate-N-acetylneuraminate (CMP-Neu5Ac) hydroxylase. Previous investigations on a limited number of tissues suggest that the activity of this enzyme governs the extent of glycoconjugate sialylation with
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