341600

Fibrinogen, Fragment D, Human Plasma

Fibrinogen fragment D is a thermolabile native human plasma protein prepared by digestion of purified fibrinogen followed by preparative electrophoresis.

• UNSPSC 코드: 12352202
• NACRES: NA.41

속성

• Quality Level: 200
• 형태: lyophilized
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• 불순물: ≤1% Fragment E
• solubility: sterile distilled water: 200 μg/mL
• 배송 상태: ambient
• 저장 온도: −20°C

설명

일반 설명

Native fibrinogen fragment D from human plasma prepared by plasmin digestion of purified fibrinogen followed by preparative electrophoresis. Thermolabile core fragment of fibrinogen. Complete proteolysis of a single fibrinogen molecule produces two D and one E fragments. The D and E fragments have no common antigenic determinants; therefore, no cross-reaction occurs. Reported to increase endothelial membrane permeability to albumin.

Native fibrinogen fragment D from human plasma prepared by plasmin digestion of purified fibrinogen followed by preparative electrophoresis. Thermolabile fragment. Complete proteolysis of a single fibrinogen molecule produces two D and one E fragments. Fragment D has been shown to increase endothelial monolayer permeability and to decrease polymorphonuclear leukocyte adhesion to endothelial cells. The D and E fragments have no common antigenic determinants; therefore, no cross-reactivity occurs.

경고

Toxicity: Standard Handling (A)

물리적 형태

Lyophilized from 400 mM glycine, 150 mM NaCl.

재구성

Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 4 h at 20°C or for up to 8 h at 4°C or for up to 3 months at -70°C.

분석 메모

single band by SDS-PAGE

기타 정보

Spraggon, G., et al. 1997. Nature 389, 455.
Stirk, C.M., et al. 1993. Atherosclerosis103, 159.
Vogel, P., et al. 1993. Eur. Surg. Res.25, 83.
Azpiazu, I., and Chapman, D. 1992. Biochim. Biophys. Acta1119, 268.
Thompson, W.D., et al. 1992. J. Pathol.168, 47.
Fisher, E.G., et al. 1991. Haemostasis21, 141.
Ge, M., et al. 1991. Am. J. Physiol.261, L283.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable