33-036

PI 3-Kinase HTRF^® Assay; 10,000 wells

The PI 3-Kinase HTRF Assay is a high-performance assay kit that provides a universal method for testing all Class I PI3-Kinases in a homogeneous format. This pack size has a screening capacity of 10,000 wells.

• UNSPSC 코드: 12161503
• eCl@ss: 32161000
• NACRES: NA.84

속성

• Quality Level: 100
• 종 반응성: mouse, human
• 제조업체/상표: HTRF^®; Upstate^®
• 기술: activity assay: suitable (kinase)
• NCBI 수납 번호: NM_006218.2
• UniProt 수납 번호: P42336
• 검출 방법: fluorometric (HTRF)
• 배송 상태: dry ice
• 유전자 정보: human ... PIK3CA(5290)

설명

일반 설명

Phosphoinositide (PI) 3-kinase (PI3K) is a heterodimeric lipid kinase containing regulatory and catalytic subunits. It catalyzes the phosphorylation at the 3-position hydroxyl group of the inositol ring of phosphatidylinositol (PtdIns). PI3K is implicated in various cellular functions such as cell growth, proliferation, motility, differentiation, survival, apoptosis, cytoskeletal rearrangement, and intracellular trafficking. It also plays a vital role in glucose uptake triggered by insulin.

애플리케이션

PI 3-Kinase HTRF^® Assay; 10,000 wells has been used for measuring the enzymatic activity of the class I phosphoinositide (PI) 3-kinase isoforms by a time-resolved fluorescence resonance energy transfer (TR-FRET) assay.

생화학적/생리학적 작용

Target Sub-Family: PI3K/PI4K

포장

Kit capacity: 10,000 wells

성분

4X Reaction Buffer

PIP2 (Substrate; 1mM stock)

Stop Reagent A

Stop Reagent B

DM A Detection Reagent

DM B Detection Reagent

DM C Detection Reagent

저장 및 안정성

12 months at -70°C

법적 정보

HTRF is a registered trademark of Cis Bio International

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.