추천 제품
Quality Level
분석
≥90% (SDS-PAGE)
형태
liquid
제조업체/상표
Calbiochem®
저장 조건
OK to freeze
avoid repeated freeze/thaw cycles
불순물
IgG, IgA, IgM, C5, Factor H, or Factor I, trace
배송 상태
wet ice
저장 온도
−70°C
일반 설명
Native, human C3b complement component. Cleavage of the C3-α chain at peptide bond 77 by either of the complement C3 convertase enzymes results in production of C3a (M.W. 9083) and C3b (M.W. 180,000) fragments. The C3b fragment is a glycoprotein composed of the modified C3-α chain (α′) (M.W. 105,000) and the intact C3-β chain (M.W. 75,000). Nascent C3b has the transient ability to form a covalent ester bond with a variety of target surfaces. Once bound to target surfaces C3b becomes an essential subunit of both the classical and alternative pathway C5 cleaving enzymes. In addition, surface-bound C3b has opsonic and immune adherence activities which are mediated via binding to CR1 (CD35) complement receptors.
경고
Toxicity: Standard Handling (A)
물리적 형태
In PBS, pH 7.2, filtered through a 0.22 µm filter.
제조 메모
Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
재구성
Following initial thaw, aliquot and freeze (-70°C).
기타 정보
Wong, W.W. and Fearon, D.T. 1987. Methods Enzymol.150, 579.
Arnout, M.A., et al. 1981. J. Immunol.127, 1348.
Arnout, M.A., et al. 1981. J. Immunol.127, 1348.
법적 정보
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
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