178221

α₂-Antiplasmin, Human Plasma

A 452-amino acid glycoprotein present in plasma at about 70 µg/ml.

• 동의어(들): α₂-Protease Inhibitor, Primary Plasmin Inhibitor
• UNSPSC 코드: 12352202
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥95% (SDS-PAGE)
• 양식: solid
• 특이 활성도: ≥5 IU/mg protein
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• 배송 상태: ambient
• 저장 온도: −20°C

설명

일반 설명

A 452-amino acid glycoprotein present in plasma at about 70 µg/ml. Efficiently inhibits the plasminogen activator-induced lysis of fibrin clots. Forms a covalent complex with plasmin and inactivates it.

생화학적/생리학적 작용

Cell permeable: no

Primary Target
Plasminogen activator-induced lysis of fibrin clots

Product does not compete with ATP.

Reversible: no

경고

Toxicity: Standard Handling (A)

단위 정의

One Inhibitory Unit (I.U.) is defined as the amount of enzyme that will inhibit 1 unit plasmin activity using tosyl-Gly-Pro-Lys-pNA as substrate at 25°C, pH 7.8

물리적 형태

Lyophilized from 200 mM NaCl, 20 mM Bis-Tris, pH 6.4.

제조 메모

Please refer to the vial label for the lot-specific reconstitution volume.

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

재구성

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

기타 정보

Schaefer, B.M., et al. 1996. Arch. Dermatol. Res. 288, 122.
Aoki, N., et al. 1980. Blood 55, 483.
Saito, H., et al. 1974. Circ. Res.34, 641.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable