171372

Amphiregulin, Human, Recombinant

Amphiregulin, Human, Recombinant, consisting of amino acids 101-198 and is expressed in E. coli. Stimulates the proliferation of various human and mouse keratinocytes.

• 동의어(들): Schwannoma-derived growth factor (SDGF)
• UNSPSC 코드: 12352203
• NACRES: NA.77

속성

• 재조합: expressed in E. coli
• Quality Level: 100
• 분석: ≥97% (SDS-PAGE)
• 양식: liquid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• 불순물: <1.0 EU/μg protein Endotoxin
• 배송 상태: ambient
• 저장 온도: −20°C

설명

일반 설명

Recombinant, human amphiregulin (AR) consisting of amino acids 101-198 and expressed in E. coli. Human amphiregulin is able to stimulate the proliferation of various human and mouse keratinocytes, mammary epithelial cells, and some fibroblasts. Shown to be an autocrine growth factor, amphiregulin is also a growth inhibitor for various tumor cells and can bind to the EGF receptor.

생화학적/생리학적 작용

ED₅₀ = 5-15 ng/ml as measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblasts.

경고

Toxicity: Standard Handling (A)

물리적 형태

Lyophilized from 0.2 µm sterile-filtered PBS, BSA.

재구성

Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.

Reconstitute to 100 µg/ml in sterile PBS containing at least 0.1% human or bovine serum albumin.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3