164598

Aminopeptidase M, Porcine Kidney

• 동의어(들): Aminopeptidase M, Porcine Kidney, Alanyl aminopeptidase, Aminopeptidase M, Aminopeptidase N
• CAS Number: 9054-63-1
• 효소 위원회 번호: 3.4.11.2 (BRENDA, IUBMB)
• MDL number: MFCD00131501
• UNSPSC 코드: 12352202
• NACRES: NA.54

속성

• 생물학적 소스: Porcine kidney
• Quality Level: 100
• 양식: suspension (crystalline)
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• 색상: white
• solubility: physiological buffer: soluble; water: soluble
• 외래 활성: Oxidases ≤3%
• 배송 상태: ambient
• 저장 온도: 2-8°C

설명

일반 설명

Aminopeptidase M (APM) is abundantly found in brush border membranes of the kidney, small intestine, placenta, and liver. It is a type II integral membrane protein, known as ectoenzyme.

애플리케이션

Aminopeptidase M, porcine kidney has been used:

• to test and identify the peaks containing d-residue in the allatotropin-related peptide (ATRP)
• to study its oxidative inactivation of enzyme activity, and to screen MIRA ingredients
• for the proteolysis of isolevuglandins (IsoLGs) proteins

생화학적/생리학적 작용

Aminopeptidase M (APM) is implicated in terminating the actions of certain neuropeptides, like the enkephalins and angiotensin III in the brain. It also metabolizes specific vasoactive peptides. It functions as a receptor for certain viruses, such as coronavirus 229E. APM is a nonspecific peptidase, which rapidly breaks down l-residue peptides.

포장

Please refer to vial label for lot-specific concentration.

경고

Toxicity: Harmful (C)

단위 정의

One unit is defined as the amount of enzyme that will hydrolyze 1 µmol of Leu-pNA per min at 37°C, pH 7.2.

물리적 형태

Crystalline suspension in 3.2 M (NH₄)₂SO₄, 10 mM MgCl₂, 10 mM Tris-HCl, pH 7.5.

기타 정보

Wachsmuth, E.E., et al. 1966. Biochemistry5, 169.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable