14-602-M

PI3 Kinase (p110α/p85α) Protein, active, 20 µg

Active complex of N-terminal His6-tagged recombinant full-length human p110α & untagged, recombinant, full length, human p85α. For use in Kinase Assays.

• 동의어(들): Active PI3 Kinase Protein, PI3 Kinase p110α/p85α
• UNSPSC 코드: 12352202
• eCl@ss: 32160405
• NACRES: NA.26

속성

• 생물학적 소스: human
• Quality Level: 100
• 재조합: expressed in baculovirus infected Sf21 cells
• 분자량: M_w 125.3 kDa (p110α); M_w 83.7 kDa (p85α)
• 제조업체/상표: Upstate^®
• 기술: activity assay: suitable (kinase)
• NCBI 수납 번호: NM_006218.2
• UniProt 수납 번호: P42336
• 유전자 정보: human ... PIK3CA(5290)

설명

일반 설명

Product Source: Coexpressed by baculovirus in Sf21 insect cells

Research area: Cell signaling

Protein Target: PI3Kα/p85α Target Sub-Family: PI3K/PI4K

Complex of N-terminal His6-tagged recombinant full-length human p110α and untagged, recombinant, full length, human p85α

애플리케이션

PI3 Kinase (p110α/p85α) Protein has been used in in vitro kinase assay.

생화학적/생리학적 작용

Phosphoinositide 3-kinases (PI3Ks) are enzymes that play a crucial role in cell signaling. They are responsible for activating signaling pathways that regulate important cellular processes such as cell survival, proliferation, protein synthesis, cell metabolism, cytoskeletal rearrangements, and vesicle trafficking. PI3Ks exhibits both lipid kinase activity (phosphorylation of inositol ring in phosphatidylinositol (PtdIns) lipids) and protein kinase activity (including autophosphorylation).

포장

Also available in 250μg size as catalog # 14-602M - Call for pricing and availability.

품질

routinely evaluated by PIProfiler

물리적 형태

Ni²⁺/NTA-agarose

저장 및 안정성

6 months at -70°C

기타 정보

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.