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Merck
모든 사진(2)

Key Documents

1.07730

Supelco

Silica gel 60 GF254

for thin-layer chromatography

동의어(들):

Silica gel

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About This Item

CAS Number:
MDL number:
UNSPSC 코드:
41115711
EC 인덱스 번호:
231-545-4
NACRES:
NB.21

material

silica gel 60 matrix

Quality Level

형태

powder

효능

>5000 mg/kg LD50, skin (Rabbit)

특징

binder Gypsum
fluorescent indicator

포장

pkg of 25 kg

기술

thin layer chromatography (TLC): suitable

입자 크기

5-40 μm

공극 크기

60 Å medium pore diameter

pH

7 (20 °C, 100 g/L in H2O, slurry)

bp

2230 °C

mp

>1600 °C

벌크 밀도

200‑800 kg/m3

저장 온도

no temp limit

SMILES string

O=[Si]=O

InChI

1S/O2Si/c1-3-2

InChI key

VYPSYNLAJGMNEJ-UHFFFAOYSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Standardized sorbents ensure reliable results every time. Our broad spectrum meets all kinds of needs. In TLC, silica gel 60 sorbent is considered the most versatile. Our assortment of silica gel 60 features different grades with particle sizes ranging from 5-40 µm: silica with a gypsum binder, silica with no foreign binder, and silica gel with a fluorescence indicator. We also offer high-quality aluminum oxide, cellulose microcrystalline, and kieselgur (also known as diatomaceous earth).

애플리케이션


  • Chromatographic Separation of the Novel Hypoglycemic Drug Mitiglinide in its Bulk Powder and Pharmaceutical Formulation: Forced Degradation and Validated Stability-Indicating HPTLC/Densitometry and HPLC/UV Methods.: This research demonstrates the use of Silica gel 60 GF254 in the chromatographic separation of Mitiglinide, providing robust methods for stability and degradation analysis crucial for regulatory compliance and quality assurance in pharmaceuticals (Eissa MS et al., 2020).

  • Quality Risk Management-Based AQbD Approach to Development of VEER Chromatography Method for the Estimation of Multiple Combined Formulations of Anti-Hypertensive Drugs.: Leveraging Silica gel 60 GF254, this study outlines a novel chromatographic method development under the Analytical Quality by Design (AQbD) framework, enhancing the reliability and efficiency of drug analysis processes (Prajapati PB et al., 2021).

  • HPTLC and Spectrophotometric Estimation of Febuxostat and Diclofenac Potassium in Their Combined Tablets.: Utilizing Silica gel 60 GF254, this study presents a high-performance thin-layer chromatographic method for simultaneous estimation of Febuxostat and Diclofenac, demonstrating the gels utility in multi-drug analysis (El-Yazbi FA et al., 2016).

  • Distribution of withaferin A, an anticancer potential agent, in different parts of two varieties of Withania somnifera (L.) Dunal. grown in Sri Lanka.: This research used Silica gel 60 GF254 in the quantification of withaferin A across different plant parts, highlighting its application in the study of pharmacologically active compounds in medicinal plants (Siriwardane AS et al., 2013).

  • Simultaneous determination of metronidazole and miconazole nitrate in gel by HPTLC.: Demonstrating the adaptability of Silica gel 60 GF254, this study provides a validated HPTLC method for analyzing metronidazole and miconazole nitrate in a topical gel, crucial for ensuring therapeutic efficacy and safety in dermatological treatments (Meshram DB et al., 2009).

분석 메모

pH-value (10% suspension): 6.0 - 7.0
Fe (Iron): ≤ 0.02%
Calcium sulfate (CaSO₄·0.5 H₂O): 12.0 - 13.5%
Particle size: 90% <55 µm
Application test: conforms
UV absorption (Dichloro methane extract): conforms
The data to the particle size are related to the pure Silica gel before additive addition.

Storage Class Code

13 - Non Combustible Solids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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