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Merck
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Key Documents

1.07164

Sigma-Aldrich

Paraffin pastilles

solidification point about 56-58°C for histology

동의어(들):

Paraffin pastilles, Paraffin pastilles solidification point, Paraffin for Histology

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About This Item

CAS Number:
UNSPSC 코드:
41116124
EC 인덱스 번호:
265-154-5

Quality Level

형태

solid

효능

>5000 mg/kg LD50, oral (Rat)
>3000 mg/kg LD50, skin (Rabbit)

색상

white

kinematic viscosity

4.2 cSt(100 °C)

전이 온도

flash point >100 °C

density

0.9 g/cm3 at 20 °C

응용 분야

diagnostic assay manufacturing
hematology
histology

저장 온도

15-25°C

일반 설명

Paraffin pastilles - solidification point about 56-58 °C for histology, are a highly pure ready-to-use paraffin product. Paraffins are the materials generally used to embed the specimens for histological applications. In order to achieve uniformous ribbon-sectioning quality, defined hardness and homogeneity of the processed material is necessary. This can be guarranteed through high-quality raw materials and defined melting points. The melting point of Paraffin is 56-58°C. It is registered as IVD and CE certified product and can be used for clinical diagnostics. For more details, please see instructions for use (IFU).

애플리케이션


  • Clinical application of targeted tumour sequencing tests for detecting ERBB2 amplification and optimizing anti-HER2 therapy in gastric cancer.: This study demonstrates the use of paraffin-embedded tissue samples in targeted tumor sequencing to identify patients suitable for anti-HER2 therapy, highlighting paraffin′s utility in preserving sample integrity for genetic analysis (Ichikawa et al., 2024).

  • Novel FFPE proteomics method suggests prolactin induced protein as hormone induced cytoskeleton remodeling spatial biomarker.: Describes a novel proteomics method using formalin-fixed paraffin-embedded (FFPE) samples to identify biomarkers for hormone-induced changes in cellular structures, advancing tissue-specific molecular diagnostics (Faktor et al., 2024).

  • TSWIFT, a novel method for iterative staining of embedded and mounted human brain sections.: Introduces TSWIFT, a new technique for the iterative staining of paraffin-embedded human brain sections, providing enhanced imaging capabilities for neurological research (Porter et al., 2024).

  • [Optimal melanin removal methods for HE staining, immunohistochemistry and molecular detection].: Investigates various methods for melanin removal in HE staining processes involving paraffin-embedded samples, crucial for accurate histopathological and immunohistochemical analyses (Zhang et al., 2024).

  • Novel Histopathological Findings of Micro Bone Fragments and Epithelial Response in the Oral Mucosa in Bisphosphonate-Related Osteonecrosis of the Jaw.: This case report utilizes paraffin-embedded sections to uncover novel histopathological insights into osteonecrosis, demonstrating paraffin′s role in detailed structural analysis in pathological conditions (Koizumi et al., 2024).

Storage Class Code

11 - Combustible Solids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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