09-817

Anti-JMJD1C Antibody

from rabbit, purified by affinity chromatography

• 동의어(들): JMJD, jumonji domain containing 1C, TR-interacting protein 8, thyroid receptor interacting protein 8, probable JmjC domain-containing histone demethylation protein 2C, thyroid hormone receptor interactor 8, Thyroid receptor-interacting protein 8, Jumonji
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• 클론: polyclonal
• application: ICC; WB
• 종 반응성: human
• 기술: immunocytochemistry: suitable; western blot: suitable
• citations: 5

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: human
• 종 반응성(상동성에 의해 예측): chimpanzee (based on 100% sequence homology), rhesus macaque (based on 100% sequence homology), orangutan (based on 100% sequence homology), rabbit (based on 100% sequence homology)
• 기술: immunocytochemistry: suitable; western blot: suitable
• NCBI 수납 번호: NP_116165
• UniProt 수납 번호: Q15652
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... JMJD1C(221037)

설명

일반 설명

JMJD1C (jumonji domain-containing protein 1C) is also known as TRIP8 and mutations in this histone demethylase have been linked to certain forms of autism. JMJD1C is also thought to work in reactivating genes in embryonic stem cells, pancreatic islet and gastric cancer. JMJD1C has also been implicated as a gene expression regulator. JMJD1C with WHISTLE have recently been shown to also play a role in mouse testis development. JMJD1C has been identified as a nuclear-receptor coactivator and is a candidate gene for autism.

면역원

KLH-conjugated linear peptide corresponding to human JMJD1C.

애플리케이션

Immunocytochemistry Analysis: 1:500 dilution from a representative lot detected JMJD1C in HeLa cells.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Histone Modifying Proteins

Use Anti-JMJD1C Antibody (Rabbit Polyclonal Antibody) validated in WB, ICC to detect JMJD1C also known as jumonji domain containing 1C or TR-interacting protein 8.

품질

Evaluated by Western Blot in HeLa nuclear extract.

Western Blot Analysis: 1 µg/mL of this antibody detected JMJD1C on 10 µg of HeLa nuclear extract.

표적 설명

~284 kDa observed

물리적 형태

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
HeLa nuclear extract

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable