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Merck
모든 사진(1)

Key Documents

09-814

Sigma-Aldrich

Anti-dimethyl-Arginine Antibody, asymmetric (ASYM25)

serum, from rabbit

동의어(들):

dimethyl-arginine, asymmetric

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

항체 형태

serum

항체 생산 유형

primary antibodies

클론

polyclonal

종 반응성

mouse

종 반응성(상동성에 의해 예측)

rat (based on 100% sequence homology), human (based on 100% sequence homology)

기술

western blot: suitable

배송 상태

wet ice

타겟 번역 후 변형

unmodified

일반 설명

Asymmetrical dimethlarginine (ADMA) is an endogenous, L-arginine metabolite arising from the proteolysis of methylated arginine containing proteins and is a known inhibitor of nitric oxide synthase (NOS). In various studies, ADMA has been observed as having a regulatory role in cell motility and the actin cytoskeleton. Elevated levels of ADMA are associated with sporadic FSGS, coronary artery disease, hypertension, peripheral arterial occlusive disease, obesity, stroke, preeclampsia, and cardiovascular mortality/morbidity in patients with diabetic nephropathy.

특이성

This antibody recognizes dimethylated arginines.

면역원

KLH-conjugated linear peptide containing asymmetric dimethyl-arginine-glycine repeats.

애플리케이션

Detect dimethyl-Arginine using this Anti-dimethyl-Arginine Antibody, asymmetric (ASYM25) validated for use in WB.

품질

Evaluated by Western Blot in PRMT1 treated and untreated MEF cell lysates.

Western Blot Analysis: 1:1,000 dilution of this antibody detected dimethyl-Arginine on 10 µg of PRMT1 treated and untreated MEF cell lysates.

표적 설명

Multiple. This antibody detects proteins containing asymmetrical dimethylated arginines.

분석 메모

Control
PRMT1 treated and untreated MEF cell lysates

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1


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