09-071

Anti-G9a (BAT8) Antibody

from rabbit, purified by affinity chromatography

• 동의어(들): G9A histone methyltransferase, H3-K9-HMTase 3, HLA-B associated transcript 8, HLA-B-associated transcript 8, Histone H3-K9 methyltransferase 3, Lysine N-methyltransferase 1C, Protein G9a, ankyrin repeat-containing protein, chromosome 6 open reading frame
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: human, mouse
• 종 반응성(상동성에 의해 예측): canine, rat
• 기술: western blot: suitable
• NCBI 수납 번호: NP_006700.3
• UniProt 수납 번호: Q96KQ7
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... EHMT2(10919) ; mouse ... Ehmt2(110147) ; rat ... Ehmt2(361798)

설명

일반 설명

G9a (BAT8 or Histone-lysine N-methyltransferase) is thought to be involved in intracellular protein-protein interaction and is a lysine-preferring histone methyltransferase. H3 Lys-9 methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. The presence of the ankyrin repeats also suggests that G9a is involved in intracellular protein-protein interaction. Like Suv39h1, G9a transfers methyl groups to the lysine residues of histone H3, but with a 10- to 20-fold higher activity. G9a is localized to the nucleus but not in the repressive chromatin domains of centromeric loci, in which Suv39h1 family proteins were localized. This protein is probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. G9a also methylates histone H1.

특이성

This antibody recognizes G9a (BAT8).

면역원

KLH-conjugated linear peptide corresponding to G9a (BAT8).

애플리케이션

Anti-G9a (BAT8) Antibody is a rabbit polyclonal antibody for detection of G9a (BAT8) also known as G9A histone methyltransferase ,H3-K9-HMTase 3 ,HLA-B associated transcript 8 & has been validated in WB.

Western Blot Analysis (SNAP ID Technique): 1 µg/mL from a previous lot detected G9a (BAT8) on 10 µg of HeLa cell lysate.

품질

Evaluated by Western Blot in HeLa cell lysate.
Western Blot Analysis: : 0.25-2 µg/mL of this antibody detected G9a (BAT8) in 10 µg of HeLa cell lysate.

표적 설명

~160 kDa

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable