07-839

Anti-phospho-IR/IGF1R (Tyr1158) Antibody

Upstate^®, from rabbit

• 동의어(들): CD220, Insulin Receptor / CD221, Insulin-like Growth Factor 1 Receptor
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: human
• 제조업체/상표: Upstate^®
• 기술: immunocytochemistry: suitable; immunohistochemistry: suitable; western blot: suitable
• 동형: IgG
• NCBI 수납 번호: NM_000208.2; NM_001079817.1
• UniProt 수납 번호: P06213
• 배송 상태: dry ice
• 타겟 번역 후 변형: phosphorylation (pTyr1158)
• 유전자 정보: human ... INSR(3643)

설명

일반 설명

diabetes, insulin signaling, glucose

특이성

Human phospho-Insulin Receptor (IR) Tyrosine 1158 and Insulin-like Growth Factor 1 Receptor (IGF1R) Tyr 1131. Mouse and rat reactivity are expected based on 100% sequence homology.

Predicted to cross-react with mouse and rat based on 100% sequence homology, but have not been tested.

면역원

Peptide corresponding to the amino acid region encompassing the human, mouse, and rat phospho-Insulin Receptor (IR) Tyrosine 1158 and Insulin-like Growth Factor 1 Receptor (IGF1R) Tyr 1131.

애플리케이션

Detect phospho-IR/IGF1R (Tyr1158) using this Anti-phospho-IR/IGF1R (Tyr1158) Antibody validated for use in IC, IH & WB.

Immunoblot Analysis: A 1:1,000 dilution of this lot detected phospho-IR/IGF1R (Tyr1158) in RIPA lysate of untreated or insulin treated CHO cells transfected with IR.

Research Category
Signaling

Research Sub Category
Insulin/Energy Signaling

표적 설명

155 kDa

물리적 형태

100 μL of affinity purified rabbit polyclonal IgG in 50% storage buffer (PBS (without Mg²⁺ and Ca²⁺), pH 7.3 containing 1.0 mg/mL BSA (IgG, protease free) and 0.05% sodium azide) and 50% glycerol.

Affinity purified

저장 및 안정성

Stable for 2 years at -20°C from date of shipment.
Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerolcontaining solutions to become frozen during storage.

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable