추천 제품
생물학적 소스
rabbit
Quality Level
항체 형태
affinity purified immunoglobulin
항체 생산 유형
primary antibodies
클론
polyclonal
정제법
affinity chromatography
종 반응성
mouse, human
종 반응성(상동성에 의해 예측)
rat (based on 100% sequence homology)
제조업체/상표
Upstate®
기술
immunocytochemistry: suitable
immunofluorescence: suitable
western blot: suitable
동형
IgG
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
타겟 번역 후 변형
phosphorylation (pTyr1230/pTyr1234/pTyr1235)
유전자 정보
human ... MET(4233)
mouse ... Met(17295)
rat ... Met(24553)
특이성
Recognizes Met phosphorylated on both Tyr1234/Tyr1235 and Tyr1230/Tyr1234/Tyr1235.
면역원
Peptide corresponding to amino acid region encompassing the human, mouse, and rat phospho-c-Met (Tyr1230/Tyr1234/Tyr1235)
애플리케이션
Anti-phospho-Met (Tyr1230/Tyr1234/Tyr1235) Antibody is an antibody against phospho-Met (Tyr1230/Tyr1234/Tyr1235) for use in IC, IF & WB.
Immunoblot Analysis: A 1:1000 dilution of this lot detected phospho-Met (Tyr1230/Tyr1234/Tyr1235) in RIPA lysate of HGF treated 293T cells.
품질
Routinely evaluated by immunoblot.
표적 설명
155 kDa
법적 정보
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Mutations in the met oncogene unveil a "dual switch" mechanism controlling tyrosine kinase activity.
Federica Chiara et al.
The Journal of biological chemistry, 278(31), 29352-29358 (2003-05-15)
The met oncogene, encoding the high affinity hepatocyte growth factor receptor, is the only known gene inherited in human cancer that is invariably associated with somatic duplication of the mutant locus. Intriguingly, mutated Met requires ligand stimulation in order to
P Longati et al.
Oncogene, 9(1), 49-57 (1994-01-01)
The tyrosine kinase encoded by the MET proto-oncogene (p190MET) is the receptor for Hepatocyte Growth Factor/Scatter Factor (HGF/SF). Previous work has shown that autophosphorylation of p190MET enhances its enzymatic activity and that the major phosphorylation site is Tyr1235, located in
c-Met modulates RPE migratory response to laser-induced retinal injury.
Kasaoka, M; Ma, J; Lashkari, K
Testing null
A selective c-met inhibitor blocks an autocrine hepatocyte growth factor growth loop in ANBL-6 cells and prevents migration and adhesion of myeloma cells
Hov, H?kon, et al
Clinical cancer research : an official journal of the American Association for Cancer Research, 10, 6686-6694 (2004)
Helena L Palka et al.
The Journal of biological chemistry, 278(8), 5728-5735 (2002-12-12)
The receptor protein-tyrosine phosphatase (PTP) DEP-1 (CD148/PTP-eta) has been implicated in the regulation of cell growth, differentiation, and transformation, and most recently has been identified as a potential tumor suppressor gene mutated in colon, lung, and breast cancers. We have
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