07-502-I

Anti-p67-phox (not Human) Antibody

from rabbit, purified by affinity chromatography

• 동의어(들): Neutrophil cytosol factor 2, NCF-2, 67 kDa neutrophil oxidase factor, NADPH oxidase activator 2, Neutrophil NADPH oxidase factor 2, p67-phox, p67-phox (rodent)
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: rat, mouse
• 기술: immunohistochemistry: suitable; western blot: suitable
• NCBI 수납 번호: NP_035007
• UniProt 수납 번호: O70145
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: mouse ... Ncf2(17970) ; rat ... Ncf2(364018)

설명

일반 설명

Neutrophil cytosol factor 2 (UniProt Q09014; also known as 67 kDa neutrophil oxidase factor, NADPH oxidase activator 2, NADPH oxidase subunit 67 kDa, NCF-2, Ncf2, Neutrophil NADPH oxidase factor 2, p67-phox, p47phox) is encoded by the murine Ncf2 (also known as Noxa2, p67phox) gene in murine species (Gene ID 17970). Activation of NADPH-oxidase dependent superoxide generation requires the participation of several cytosolic factors, including p47-phox, p67-phox, p40-phox and Rac. In the resting cell p47phox, p67phox, and p40phox form a large molecular weight cytosolic complex. Activation of the NADPH oxidase is initiated by the assembly of p47phox, p67phox, and Rac with cytochrome b558 in a 1:1:1:1 complex in the plasma membrane.

면역원

Epitope: N-terminus

KLH-conjugated linear peptide corresponding to the N-terminus of mouse p67-phox.

애플리케이션

Anti-p67-phox (not Human) Antibody is an antibody against p67-phox, tested in mouse and rat, but is not expected to react with human, for use in Western Blotting and Immunohistochemistry.

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected p67-phox (rodent) in rat colon and mouse hindbrain tissue.

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

품질

Evaluated by Western Blotting in C6 and THP-1 cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected p67-phox (rodent) in 10 µg of C6 and THP-1 cell lysate.

표적 설명

~72 kDa observed. Uncharacterized band(s) may appear in some lysates.

물리적 형태

Affinity purified

Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

기타 정보

Concentration: Please refer to lot specific datasheet.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable