07-1352

Anti-acetyl STAT5B (Lys701) Antibody

from rabbit, purified by affinity chromatography

• 동의어(들): Signal transducer and activator of transcription 5B
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: human
• 기술: dot blot: suitable; western blot: suitable
• NCBI 수납 번호: NP_036580
• UniProt 수납 번호: P51692
• 배송 상태: wet ice
• 타겟 번역 후 변형: acetylation (Lys701)
• 유전자 정보: human ... STAT5B(6777)

설명

일반 설명

STAT5B (signal transducers and activators of transcription 5b) controls the expression of early response genes and takes part in cytokine signaling. Studies have linked this protein to the inhibition of NFkappaB-mediated signaling. Additional studies have shown an association of STAT5B with regulation of lactation and growth, performance, and control of adipocyte function. Constitutively active STAT5B expression is often observed in a large number of leukemia’s and solid tumors.

특이성

Other homologies: Rat and Mouse (91% sequence homology).

This antibody recognizes STAT5B acetylated at Lys701.

면역원

Epitope: Acetylated Lys701

KLH-conjugated linear peptide corresponding to human STAT5B acetylated at Lys701.

애플리케이션

Detect acetyl STAT5B (Lys701) using this Anti-acetyl STAT5B (Lys701) Antibody validated for use in DB & WB.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Transcription Factors

Western Blot Analysis: A representative lot was used by an independent laboratory in WB. (Ma, L., et al. (2010). Proc Natl Acad Sci U S A. 107(45):19314-19319.)

품질

Evaluated by Dot Blot in modified and non modified peptides of acetylated and non-acetylated STAT5B protein.

Dot Blot Analysis: 1 µg/mL of this antibody detected STAT5B in modified and non modified peptides of acetylated and non-acetylated STAT5B protein.

표적 설명

90 kDa calculated

물리적 형태

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
Modified and non modified peptides of acetylated and non-acetylated STAT5B protein

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable