07-104

Anti-IGF2 mRNA-binding protein 3 Antibody

from rabbit, purified by affinity chromatography

• 동의어(들): IGF II mRNA binding protein 3, IGF-II mRNA-binding protein 3, IGF2 mRNA-binding protein 3, KH domain containing protein overexpressed in cancer, KH domain-containing protein overexpressed in cancer, VICKZ family member 3, insulin-like growth factor 2 mRN
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: human, mouse, canine
• 종 반응성(상동성에 의해 예측): rhesus monkey (based on 100% sequence homology), dog (based on 100% sequence homology), horse (based on 100% sequence homology), chimpanzee (based on 100% sequence homology)
• 기술: western blot: suitable
• NCBI 수납 번호: NP_006538
• UniProt 수납 번호: O00425
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... IGF2BP3(10643)

설명

일반 설명

The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5′ UTR of the insulin-like growth factor 2 leader 3 mRNA and may repress translation of insulin-like growth factor 2 during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq].

특이성

This antibody recognizes IGF2 mRNA-binding protein 3 at the C-terminus.

면역원

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to human IGF2 mRNA-binding protein 3 at and around the C-terminus.

애플리케이션

Research Category
Apoptosis & Cancer

Research Sub Category
Growth Factors & Receptors

This Anti-IGF2 mRNA-binding protein 3 Antibody is validated for use in WB for the detection of IGF2 mRNA-binding protein 3.

Western Blot (SNAP ID) Analysis: 2 µg/mL from a previous lot detected IGF2 mRNA-binding protein 3 on 10 µg of Hek293 cell lysate.

Immunoprecipitation Analysis: A previous lot was used by an independent laboratory in IP.

품질

Evaluated by Western Blot in Hek293 cell lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected IGF2 mRNA-binding protein 3 on 10 µg of Hek293 cell lysate.

표적 설명

64 kDa was observed. Predicted to cross-react with all the Isoforms of IGF2BP3.

물리적 형태

Affinity purified

Purified rabbit serum in PBS with 0.09% azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
Hek293 cell lysate

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable