생물학적 소스
rabbit
항체 형태
purified antibody
항체 생산 유형
primary antibodies
클론
polyclonal
종 반응성
mouse, human, rat
제조업체/상표
Upstate®
기술
western blot: suitable
동형
IgG
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... HDAC5(10014)
특이성
HDAC5
면역원
KLH-conjugated synthetic peptides corresponding to amino acids 536-545 and 194-206 (C-TKTGELPRQP and C-KSKEPTPGGLNHS) of human HDAC5
애플리케이션
Detect HDAC5 also known as histone deacetylase 5 with Anti-HDAC5 Antibody (Rabbit Polyclonal Antibody), that has been demonstrated to work in WB.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Histones
Histones
Weaker staining noticed in mouse and rat versus human.
품질
routinely evaluated by immunoblot on HeLa nuclear extract or HeLa whole cell lysate
표적 설명
160 kDa
물리적 형태
0.1M Tris-glycine, pH 7.4, 0.15M NaCl and 0.05% sodium azide.
Format: Purified
Protein A chromatography
저장 및 안정성
Stable for 1 year at 2-8°C from date of receipt.
법적 정보
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Proteomic analyses of intermediate filaments reveals cytokeratin8 is highly acetylated--implications for colorectal epithelial homeostasis.
Sian H Leech,Caroline A Evans,Leila Shaw,Chi H Wong,Joanne Connolly,John R Griffiths et al.
Proteomics null
Hongbo Ling et al.
Cell cycle (Georgetown, Tex.), 11(20), 3779-3791 (2012-10-02)
Centrosome duplication is controlled both negatively and positively by a number of proteins. The activities and stabilities of those regulatory proteins are in many cases controlled by posttranslational modifications. Although acetylation and deacetylation are highly common posttranslational modifications, their roles
Lauren E Kernochan et al.
Human molecular genetics, 14(9), 1171-1182 (2005-03-18)
Increasing survival motor neuron 2 (SMN2) gene expression may be an effective strategy for the treatment of spinal muscular atrophy (SMA). Histone deacetylase (HDAC) inhibitors have been shown to increase SMN transcript and protein levels, but the specific role of
Oliver H Krämer et al.
The EMBO journal, 22(13), 3411-3420 (2003-07-04)
Histone-modifying enzymes play essential roles in physiological and aberrant gene regulation. Since histone deacetylases (HDACs) are promising targets of cancer therapy, it is important to understand the mechanisms of HDAC regulation. Selective modulators of HDAC isoenzymes could serve as efficient
Syed A H Zaidi et al.
Investigative ophthalmology & visual science, 61(11), 17-17 (2020-09-12)
We determined whether δ-opioid receptor agonist (SNC-121) regulates acetylation homeostasis via controlling histone deacetylases (HDACs) activity and expression in optic nerve head (ONH) astrocytes. ONH astrocytes were treated with SNC-121 (1 µM) for 24 hours. The HDAC activity was measured
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