추천 제품
생물학적 소스
mouse
Quality Level
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
JBW502, monoclonal
종 반응성
human
제조업체/상표
Upstate®
기술
western blot: suitable
동형
IgG
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
타겟 번역 후 변형
phosphorylation (pSer78)
유전자 정보
human ... HSPB2(3316)
특이성
phosphorylated HSP27 (Ser78)
면역원
peptide corresponding to amino acids 73-83 of human HSP27 with a C-terminus cysteine added for conjugation (YSRAL[pS]RQLSS-C)
애플리케이션
Anti-phospho-HSP27 (Ser78) Antibody, clone JBW502 is an antibody against phospho-HSP27 (Ser78) for use in WB.
Research Category
Protein Trafficking
Protein Trafficking
Research Sub Category
Chaperones
Chaperones
품질
routinely evaluated by immunoblot on phosphorylated HSP27 in 20mg of a cell lysate prepared from MCF-7 cells that were heat shocked for 30 minutes at 42°C, cultured for an additional 16 hours at 37°C, and then stimulated with 200mM arsenite for 30 minutes
표적 설명
27kDa
결합
Replaces: 04-447
물리적 형태
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein G Chromatography
저장 및 안정성
2 years at -20°C
법적 정보
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Heat shock protein 27 association with the I kappa B kinase complex regulates tumor necrosis factor alpha-induced NF-kappa B activation.
Park, KJ; Gaynor, RB; Kwak, YT
The Journal of Biological Chemistry null
Phosphorylation of Ser78 of Hsp27 correlated with HER-2/neu status and lymph node positivity in breast cancer.
Zhang, D; Wong, LL; Koay, ES
Molecular Cancer null
Eugene Chang et al.
Blood, 117(8), 2527-2537 (2010-12-07)
Actin filament remodeling regulates several endothelial cell (EC) processes such as contraction, migration, adhesion, and shape determination. Mitogen-activated protein kinase (MAPK)-activated protein kinase 2 (MK2)-mediated phosphorylation of heat-shock protein 27 kDa (HSP27) promotes actin filament remodeling, but little is known
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