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Merck
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Key Documents

05-168

Sigma-Aldrich

Anti-TNFα Antibody, clone MPG-XT3

clone MPG-XT3, Upstate®, from rat

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rat

Quality Level

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

MPG-XT3, monoclonal

종 반응성

mouse

제조업체/상표

Upstate®

기술

neutralization: suitable

동형

IgG1

NCBI 수납 번호

UniProt 수납 번호

배송 상태

dry ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... TNF(7124)

일반 설명

The concentration of antibody needed to neutralize the bioactivity of TNF-α will depend on the cell type, the incubation conditions, and the biological response studied.

특이성

mouse TNF-α; does not recognize human or rat TNF-α

면역원

Recombinant murine TNF-α

애플리케이션

Research Category
Signaling
Research Sub Category
Growth Factors & Receptors
This Anti-TNFalpha Antibody, clone MPG-XT3 is validated for use in NEUT for the detection of TNFα.

품질

routinely used to neutralize 50% of the cytotoxic effect of recombinant mouse TNF-α on actinomycin D treated L929 cells.

표적 설명

17 kDa

결합

Replaces: 04-1114

물리적 형태

0.01M Tris-glycine, 0.15M NaCl, pH 7.4
DEAE chromatography
Format: Purified

저장 및 안정성

2 years at -20°C

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Cytokine mRNA in the central nervous system of SCID mice infected with Toxoplasma gondii: importance of T-cell-independent regulation of resistance to T. gondii.
Hunter, C A, et al.
Infection and Immunity, 61, 4038-4044 (1993)
J A Guevara Patiño et al.
Journal of immunology (Baltimore, Md. : 1950), 164(4), 1689-1694 (2000-02-05)
Apoptosis is one of the key regulatory mechanisms in tissue modeling and development. In the thymus, 95-98% of all thymocytes die by apoptosis because they failed to express a TCR with an optimal affinity for the selecting intrathymic peptide-MHC complexes.
C K Yu et al.
International archives of allergy and immunology, 112(1), 73-82 (1997-01-01)
Dermatophagoides farinae (Der f) is one of the most common species of dust mites that induce asthma and allergic rhinitis. We have reported that Der f challenge on sensitized mice elicited a distinct type of hypersensitivity, called early-type hypersensitivity (ETH)
A Kunitz-type protease inhibitor, bikunin, inhibits ovarian cancer cell invasion by blocking the calcium-dependent transforming growth factor-beta 1 signaling cascade
Kobayashi, H., et al
The Journal of Biological Chemistry, 278, 7790-7799 (2003)
Role of laminin-1, collagen IV, and an autocrine factor(s) in regulated secretion by lacrimal acinar cells.
L Chen, J D Glass, S C Walton, G W Laurie
The American Journal of Physiology null

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