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Merck
모든 사진(2)

주요 문서

05-149

Sigma-Aldrich

Anti-FGFR1 Antibody, clone 19B2

clone 19B2, Upstate®, from mouse

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모든 사진(2)

About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

100

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

19B2, monoclonal

종 반응성

human, rat

제조업체/상표

Upstate®

기술

immunoprecipitation (IP): suitable
western blot: suitable

동형

IgG1

NCBI 수납 번호

NM_015850.3
NM_023105.2
NM_023106.2
NM_023107.2
NM_023108.2
NM_023110.2
NM_023111.2

UniProt 수납 번호

P11362

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... FGFR1(2260)

특이성

extra cellular domain for both (alpha and beta) human FGF receptor

면역원

E. coli fusion protein corresponding to amino acids 23-325 of human FGF receptor beta (Flg)

애플리케이션

Anti-FGFR1 Antibody, clone 19B2 detects level of FGFR1 & has been published & validated for use in IP & WB.
Research Category
Signaling
Research Sub Category
Growth Factors & Receptors

품질

routinely evaluated in sFGFR-1 (obtained from Alexis Biochemicals, Catalog # SFC-015)

표적 설명

110 kDa

물리적 형태

0.1M Tris-glycine, pH 7.4, 0.15M NaCl containing 0.05% sodium azide
Format: Purified
Protein G Chromatography

저장 및 안정성

2 years at -20°C or 2 months at 4°C

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

J Z Hou et al.
Science (New York, N.Y.), 251(4994), 665-668 (1991-02-08)
Changes in heparin-binding fibroblast growth factor gene expression and receptor phenotype occur during liver regeneration and in hepatoma cells. The nucleotide sequence of complementary DNA predicts that three amino-terminal domain motifs, two juxtamembrane motifs, and two intracellular carboxyl-terminal domain motifs
Suppression of fibroblast growth factor receptor signaling inhibits pancreatic cancer growth in vitro and in vivo.
M Wagner, M E Lopez, M Cahn, M Korc
Gastroenterology null
X Guillonneau et al.
Molecular biology of the cell, 9(10), 2785-2802 (1998-10-08)
Fibroblast growth factors (FGF) 1 and 2 and their tyrosine kinase receptor (FGFR) are present throughout the adult retina. FGFs are potential mitogens, but adult retinal cells are maintained in a nonproliferative state unless the retina is damaged. Our work
Expression and immunochemical analysis of rat and human fibroblast growth factor receptor (flg) isoforms.
Xu, J, et al.
The Journal of Biological Chemistry, 267, 17792-17803 (1992)
Y Mazaki et al.
Molecular biology of the cell, 12(3), 645-662 (2001-03-17)
Paxillin acts as an adaptor protein in integrin signaling. We have shown that paxillin exists in a relatively large cytoplasmic pool, including perinuclear areas, in addition to focal complexes formed at the cell periphery and focal adhesions formed underneath the
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