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Merck
모든 사진(1)

주요 문서

04-478

Sigma-Aldrich

Anti-phospho-STAT1 (Ser 727) Antibody, clone 12C5

clone 12C5, Upstate®, from mouse

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모든 사진(1)

About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

100

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

12C5, monoclonal

종 반응성

human

제조업체/상표

Upstate®

기술

ELISA: suitable
western blot: suitable

동형

IgG1

NCBI 수납 번호

NM_007315.2
NM_139266.1

UniProt 수납 번호

P42224

배송 상태

wet ice

타겟 번역 후 변형

phosphorylation (pSer727)

유전자 정보

human ... STAT1(6772)

특이성

Recognizes phosphorylated domain of STAT1 on Serine727

면역원

KLH-conjugated synthetic peptide encompassing the surrounding amino acids of Serine727 on phosphorylated STAT1

애플리케이션

Anti-phospho-STAT1 (Ser 727) Antibody, clone 12C5 is a Mouse Monoclonal Antibody for detection of phospho-STAT1 (Ser 727) also known as signal transducer & activator of transcription 1 & has been tested in ELISA & WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors

품질

Routinely evaluated by immunoblot.

표적 설명

92 kDa

물리적 형태

Format: Purified
In 1 mL of PBS containing 0.09% sodium azide, PEG, sucrose, and 50% glycerol.
Subsequent thiophilic adsorption and size exclusion chromatography

저장 및 안정성

2 years at -20°C from date of shipment. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

시험 성적서(COA)

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문서 라이브러리 방문

Rico K H Lo et al.
Cellular signalling, 18(3), 307-317 (2005-06-28)
The ability of the human prostacyclin receptor (hIP) to regulate the activities of signal transducers and activators of transcription (STATs) has not yet been documented. In the present study, we have delineated the mechanism by which hIP induces STAT3 phosphorylations
VEGF receptors on chronic lymphocytic leukemia (CLL) B cells interact with STAT 1 and 3: implication for apoptosis resistance.
Lee, Y K, et al.
Leukemia, 19, 513-523 (2005)
Rama S Kota et al.
The Journal of biological chemistry, 280(35), 31076-31084 (2005-07-05)
Lipoprotein lipase (LPL) is a key enzyme in the hydrolysis of triglyceride-rich lipoproteins. In vascular diseases, such as atherosclerosis, inflammation plays an important role in the pathogenesis of the disease. We examined the role of LPL in modulating tumor necrosis
H Nguyen et al.
The Journal of biological chemistry, 276(36), 33361-33368 (2001-07-05)
STAT1 must be phosphorylated on serine 727 to be fully active in transcription. We show that phosphatidylinositol 3-kinase (PI3K) and its effector kinase Akt play an important role in the serine phosphorylation of STAT1 and in the activation of gene

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