04-1551

Anti-SMRT Antibody, clone 1SM-1E7

ascites fluid, clone 1SM-1E7, from mouse

• 동의어(들): CTG repeat protein 26, Silencing mediator of retinoic acid and thyroid hormone receptor, T3 receptor-associating factor, Thyroid-, retinoic-acid-receptor-associated corepressor, nuclear receptor co-repressor 2, silencing mediator for retinoid and thyroid
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 항체 형태: ascites fluid
• 항체 생산 유형: primary antibodies
• 클론: 1SM-1E7, monoclonal
• 종 반응성: mouse, rat, human
• 기술: western blot: suitable
• 동형: IgG2aκ
• NCBI 수납 번호: NP_001070729.1
• UniProt 수납 번호: Q9Y618
• 배송 상태: dry ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... NCOR2(9612) , TRAC(28755)

설명

일반 설명

The Silencing mediator of retinoic acid & thyroid hormone receptor protein, commonly called the SMRT protein mediates the transcriptional repression of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription machinery. Consistent with this activity, this protein is known to form a large corepressor complex containing SIN3A/B and histone deacetylases HDAC1 and HDAC2. SMRT is also a component of the N-Cor repressor (nuclear receptor corepressor), a multi-subunit complex minimally composed of NCOR1, NCOR2, HDAC3, TBL1X, TBL1R, CORO2A and GPS2. SMRT and nuclear receptor corepressor N-CoR are related transcriptional corepressors which contain two distinct domains capable of interacting with unliganded nuclear receptors to repress their basal transcriptional activity.

특이성

This antibody recognizes SMRT.

애플리케이션

Use Anti-SMRT Antibody, clone 1SM-1E7 (Mouse Monoclonal Antibody) validated in WB to detect SMRT also known as CTG repeat protein 26, Silencing mediator of retinoic acid & thyroid hormone receptor.

품질

Evaluated by Western Blot in human brain lysate.

Western Blot Analysis: 1:1,000 dilution of this antibody detected SMRT on 10 µg of human brain lysate.

표적 설명

~ 275 kDa

물리적 형태

Unpurified mouse monoclonal IgG2aκ ascites with 0.05% sodium azide.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable