04-1470

Anti-OX40L (CD252) Antibody, clone RM134L

clone RM134L, from rat

• 동의어(들): Tumor necrosis factor ligand superfamily member 4, OX40 ligand, OX40L, CD252
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rat
• Quality Level: 100
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: RM134L, monoclonal
• 종 반응성: mouse
• 기술: flow cytometry: suitable; immunohistochemistry: suitable
• 동형: IgG2bκ
• NCBI 수납 번호: NP_033478
• UniProt 수납 번호: P43488
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: mouse ... Tnfsf4(22164)

설명

일반 설명

OX40L (Tumor necrosis factor ligand superfamily member 4; or CD252) is the endogenous ligand of the OX40 receptor. OX40 is localized on activated T-cells and propagates the immune response by promoting division and survival of T-cells, thereby increasing the population of memory CD4 and CD8 T cells produced in response to antigen detection. The OX40/OX40L may also regulate cytokine production and suppress the activity of T-regulatory cells. OX40/OX40L is therefore an important mediator of the immune response. Previous studies have suggested that OX40 signaling maybe involved in the development of autoimmune diseases.

특이성

This antibody recognizes the extracellular domain of OX40L.

면역원

Mouse OX40L cDNA-transfected NRK cells

애플리케이션

Anti-OX40L (CD252) Antibody, clone RM134L detects level of OX40L (CD252) & has been published & validated for use in Flow Cytometry & IHC.

Immunohistochemistry Analysis: A representative lot was used by an independent laboratory in mouse lung tissue. (Hoshino, A., et al. (2003). Eur. J. Immunol. 33:861–869.)

품질

Evaluated by Flow Cytometry in mouse OX40L/L5178Y cells.

Flow Cytometry Analysis: 10 µg of this antibody detected OX40L in mouse OX40L/L5178Y cells.

표적 설명

22 kDa calculated

물리적 형태

Format: Purified

분석 메모

Control
Mouse OX40L/L5178Y cells

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable