추천 제품
양식
powder
포장
pkg of 1 × 5 mg (870851P-5mg)
제조업체/상표
Avanti Research™ - A Croda Brand 870851P
지질 유형
bioactive lipids
배송 상태
dry ice
저장 온도
−20°C
SMILES string
C[N+](C)(C)C[C@H](OC(CCCCCCCCCCCCCCC)=O)CC([O-])=O
InChI
1S/C23H45NO4/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(27)28-21(19-22(25)26)20-24(2,3)4/h21H,5-20H2,1-4H3
InChI key
XOMRRQXKHMYMOC-UHFFFAOYSA-N
일반 설명
C16 Carnitine, also called as palmitoyl L-carnitine, is an endogenous acylcarnitine. Structurally, it contains Levocarnitine (L-carnitine) head group and 16 carbon saturated fatty acid tail. Palmitoyl L-carnitine is derived by reversible reaction of palmitoyl-CoA esters with carnitine. Palmitoyl L-carnitine is transported across the inner membrane by carnitine palmitoyl transferase II for β-oxidation.
애플리케이션
C16 Carnitine or palmitoyl L-carnitine has been used to study its influence on the glycine transporters activity.
생화학적/생리학적 작용
C16 Carnitine has a potential to inhibit glycine transporter 2 (GlyT2). It acts as a key energy donor for β-oxidation. Palmitoyl carnitine activates the Ca2+ release channel of skeletal muscle sarcoplasmic reticulum. Elevated levels of palmitoyl L-carnitine due to palmitoyl transferase II deficiency causes autosomal recessive disorder of energy metabolism, which primarily affects skeletal muscle.
포장
5 mL Amber Glass Screw Cap Vial (870851P-5mg)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
가장 최신 버전 중 하나를 선택하세요:
R el-Hayek et al.
Biophysical journal, 65(2), 779-789 (1993-08-01)
Studies of [3H]ryanodine binding, 45Ca2+ efflux, and single channel recordings in planar bilayers indicated that the fatty acid metabolite palmitoyl carnitine produced a direct stimulation of the Ca2+ release channel (ryanodine receptor) of rabbit and pig skeletal muscle junctional sarcoplasmic
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