추천 제품
양식
powder
포장
pkg of 1 × 5 mg (860629P-5mg)
제조업체/상표
Avanti Research™ - A Croda Brand 860629P
지질 유형
sphingolipids
배송 상태
dry ice
저장 온도
−20°C
SMILES string
OC[C@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)[C@]([H])(O)CCCCCCCCCCCCCCC
InChI
1S/C42H83NO3/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-26-28-30-32-34-36-38-42(46)43-40(39-44)41(45)37-35-33-31-29-27-25-16-14-12-10-8-6-4-2/h17-18,40-41,44-45H,3-16,19-39H2,1-2H3,(H,43,46)/b18-17-/t40-,41+/m0/s1
InChI key
YUULKFVZRXQHPM-ATHUGRIKSA-N
애플리케이션
C24:1 Dihydroceramide has been used as a standard in quadrupole time-of-flight (Q-TOF) mass spectrometry for the measurement of sphingolipid metabolites in adipose tissue. It has also been used a standard in diacylglycerol kinase (DGK) assay to quantify dihydroceramides in CLN9-deficient cells.
생화학적/생리학적 작용
C24:1 Dihydroceramide is a synthetic dihydroceramide. Dihydroceramides are reduced to ceramides by the enzyme dihydroceramide desaturase. Elevated levels of serum 24:1 DHC has been observed in patients with history of hepatocellular carcinoma (HCC) pre-orthopic liver transplantation (OLT), compared to patients with no prior HCC. Therefore, 24:1 DHC can be used as a HCC biomarker in post-OLT patients.
포장
5 mL Amber Glass Screw Cap Vial (860629P-5mg)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
가장 최신 버전 중 하나를 선택하세요:
C22: 0-and C24: 0-dihydroceramides confer mixed cytotoxicity in T-cell acute lymphoblastic leukemia cell lines
Holliday Jr, et al.
PLoS ONE, 8(9) (2013)
The CLN9 protein, a regulator of dihydroceramide synthase
Schulz A, et al.
The Journal of Biological Chemistry, 281(5), 2784-2794 (2006)
C22: 0-and C24: 0-dihydroceramides confer mixed cytotoxicity in T-cell acute lymphoblastic leukemia cell lines
Holliday Jr, et al.
Testing, 8(9) (2013)
Adipocyte Hypoxia-Inducible Factor 2alpha Suppresses Atherosclerosis by Promoting Adipose Ceramide Catabolism
Zhang X, et al.
Cell Metabolism, 30(5), 937-951 (2019)
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