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Merck
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주요 문서

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857235P

Avanti

(2S)-OMPT

Avanti Research™ - A Croda Brand

동의어(들):

(2S)-1-(9Z-octadecenoyl)-2-O-methyl-glycero-3-phosphothionate (ammonium salt), 1-oleoyl-2-methyl-sn-glycero-3-phosphothionate (ammonium salt)

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모든 사진(3)

About This Item

실험식(Hill 표기법):
C22H46NO6PS
CAS Number:
645408-61-3
Molecular Weight:
483.64
UNSPSC 코드:
51191904

분석

≥99% (TLC)

양식

powder

포장

pkg of 1 × 25 mg (857235P-25MG)
pkg of 1 × 5 mg (857235P-5MG)

제조업체/상표

Avanti Research™ - A Croda Brand

지질 유형

phospholipids

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[NH4+].CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](COP(O)([O-])=S)OC

애플리케이션

lipids research

포장

5 mL Amber Glass Screw Cap Vial (857235P-5MG);5 mL Amber Glass Screw Cap Vial (857235P-25MG)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

49.5 °F - closed cup

Flash Point (°C)

9.7 °C - closed cup

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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Lian Qian et al.
Journal of medicinal chemistry, 46(26), 5575-5578 (2003-12-12)
The metabolically stabilized LPA analogue, 1-oleoyl-2-O-methyl-rac-glycerophosphothioate (OMPT), is a potent agonist for the LPA(3) G-protein-coupled receptor. A new enantiospecific synthesis of both (2R)-OMPT and (2S)-OMPT is described. Calcium release assays in both LPA(3)-transfected insect Sf9 and rat hepatoma Rh7777 cells
Identification of a phosphothionate analogue of lysophosphatidic acid (LPA) as a selective agonist of the LPA3 receptor.
Hasegawa Y, et al.
The Journal of Biological Chemistry, 278, 11962-11969 (2003)
Yutaka Hasegawa et al.
The Journal of biological chemistry, 278(14), 11962-11969 (2003-01-30)
Lysophosphatidic acid (LPA) is a bioactive lysophospholipid mediator that acts through G protein-coupled receptors. Most cell lines in culture express one or more LPA receptors, making it difficult to assign a response to specific LPA receptors. Dissection of the signaling
Pericytes prevent regression of endothelial cell tubes by accelerating metabolism of lysophosphatidic acid
Motiejunaite R, et al.
Microvascular Research, 93(2), 62-71 (2014)
Enantioselective responses to a phosphorothioate analogue of lysophosphatidic acid with LPA3 receptor-selective agonist activity.
Qian L, et al.
Journal of Medicinal Chemistry, 46, 5575-5578 (2003)
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