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Key Documents

850183P

Avanti

08:0 PI(3,4)P2

1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′-bisphosphate) (ammonium salt), powder

동의어(들):

PIP2[3′,4′](8:0/8:0); 110666

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About This Item

실험식(Hill 표기법):
C25H58N3O19P3
CAS Number:
Molecular Weight:
797.66
UNSPSC 코드:
51191904
NACRES:
NA.25

분석

>99% (TLC)

형태

powder

포장

pkg of 1 × 100 μg (with stopper and crimp cap (850183P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850183P-500ug))

제조업체/상표

Avanti Research - A Croda Brand 850183P

지질 유형

phospholipids
cardiolipins

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[H][C@@](COP(O[C@H]1[C@H](O)[C@@H](O)[C@H](OP(O)([O-])=O)[C@@H](OP(O)([O-])=O)[C@H]1O)([O-])=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+].[NH4+].[NH4+]

일반 설명

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.

애플리케이션

08:0 PI(3,4)P2 (1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′-bisphosphate) (ammonium salt)) has been used in hydrogen deuterium exchange mass spectrometry (HDX-MS) to compare the dynamics of full-length wild-type (WT) sorting nexin 9 (SNX9)/used in lipid mixture for SNX9 tubulation assay. It may also be used in liposomes for nanoparticle tracking analysis.

생화학적/생리학적 작용

Phosphatidylinositol 3,4,-biphosphate (PI(3,4)P2) serves as a lipid second messenger.

포장

2 mL Amber Serum Vial with Stopper and Crimp Cap (850183P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850183P-500ug)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Wen-Ting Lo et al.
Developmental cell, 43(4), 522-529 (2017-11-22)
Clathrin-mediated endocytosis occurs by bending and remodeling of the membrane underneath the coat. Bin-amphiphysin-rvs (BAR) domain proteins are crucial for endocytic membrane remodeling, but how their activity is spatiotemporally controlled is largely unknown. We demonstrate that the membrane remodeling activity
Leonardo Almeida-Souza et al.
Cell, 174(2), 325-337 (2018-06-12)
Multiple proteins act co-operatively in mammalian clathrin-mediated endocytosis (CME) to generate endocytic vesicles from the plasma membrane. The principles controlling the activation and organization of the actin cytoskeleton during mammalian CME are, however, not fully understood. Here, we show that
Gerald R V Hammond et al.
Science (New York, N.Y.), 337(6095), 727-730 (2012-06-23)
The quantitatively minor phospholipid phosphatidylinositol (4,5)-bisphosphate [PI(4,5)P(2)] fulfills many cellular functions in the plasma membrane (PM), whereas its synthetic precursor, phosphatidylinositol 4-phosphate (PI4P), has no assigned PM roles apart from PI(4,5)P(2) synthesis. We used a combination of pharmacological and chemical

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