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Merck
모든 사진(3)

주요 문서

850092P

Avanti

Brain Lyso PS

Avanti Research - A Croda Brand 850092P, powder

동의어(들):

L-α-lysophosphatidylserine (Brain, Porcine) (sodium salt)

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About This Item

CAS Number:
UNSPSC 코드:
12352211
NACRES:
NA.25

분석

>99% (LPS; may contain up to 10% of the 2-LPS isomer, TLC)

양식

powder

포장

pkg of 1 × 10 mg (850092P-10mg)
pkg of 1 × 5 mg (850092P-5mg)

제조업체/상표

Avanti Research - A Croda Brand 850092P

지질 유형

phosphoglycerides

배송 상태

dry ice

저장 온도

−20°C

SMILES string

O[C@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)([H])COC(CCCCCCCCCCCCCCCCC)=O.[Na+]

일반 설명

Lyso-phosphatidylserine (lyso-PS) is produced by the enzymatic action of phospholipase A1 and A2 on phosphatidylserine.

애플리케이션

Brain Lyso PS is suitable for use:
  • as standard to quantify lipids using ultra high performance liquid chromatography-electrospray ionization-tandem mass spectrometry (UHPLC-ESI-MS/MS)
  • in the preparation of liposomes for coating dynabeads for binding of factor H (fH)
  • as a ligand for G-protein coupled receptor 34 (GPR34) in in vitro experiments to investigate its effect granulosa cells(GC) and hormone production
  • as substrate for sicariid phospholipase D (PLD) toxins (SicTox) enzymes

생화학적/생리학적 작용

Lyso-Phosphatidylserine (Lyso-PS) plays a key role in histamine release from mast cells. Lyso-PS inhibits the growth to T cells. It is a chemotactic substance for fibroblast and tumor cells. Lyso-PS is involved in tumor progression and allergic reactions.

포장

5 mL Amber Glass Screw Cap Vial (850092P-10mg)
5 mL Amber Glass Screw Cap Vial (850092P-5mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


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시험 성적서(COA)

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문서 라이브러리 방문

이미 열람한 고객

Altered immune response in mice deficient for the G protein-coupled receptor GPR34
Liebscher I, et al.
Test, 286(3), 2101-2110 (2011)
G protein-coupled receptor 34 in ovarian granulosa cells of cattle: changes during follicular development and potential functional implications
Spicer LJ, et al.
Domestic Animal Endocrinology, 59(6), 90-99 (2017)
Ultra-high-performance liquid chromatography electrospray ionization tandem mass spectrometry for accurate analysis of glycerophospholipids and sphingolipids in drug resistance tumor cells
Li L, et al.
Journal of Chromatography A, 1381(3), 140-148 (2015)
Annexin-II, DNA, and histones serve as factor H ligands on the surface of apoptotic cells
Leffler J, et al.
Test, 285(6), 3766-3776 (2010)
Lysophosphatidylserine stimulates chemotactic migration of colorectal cancer cells through GPR34 and PI3K/Akt pathway
Iida Y, et al.
Anticancer Research, 34(10), 5465-5472 (2014)

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