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Merck
모든 사진(2)

문서

840063P

Avanti

18:0-18:2 PS

1-stearoyl-2-linoleoyl-sn-glycero-3-phospho-L-serine (sodium salt), powder

동의어(들):

1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serine (sodium salt); PS(18:0/18:2(9Z,12Z))

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About This Item

실험식(Hill 표기법):
C42H77NO10PNa
CAS Number:
Molecular Weight:
810.03
UNSPSC 코드:
51191904
NACRES:
NA.25

분석

>99% (TLC)

형태

powder

포장

pkg of 1 × 10 mg (840063P-10mg)

제조업체/상표

Avanti Research - A Croda Brand 840063P

지질 유형

cardiolipins
phospholipids

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C42H78NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h12,14,18,20,38-39H,3-11,13,15-17,19,21-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/b14-12-,20-18-;/t38-,39+;/m1./s1

InChI key

AHMHWPOYIVVEKN-PTDXFASBSA-M

일반 설명

18:0-18:2 PS or 1-stearoyl-2-linoleoyl-sn-glycero-3-phospho-L-serine is an asymmetric polyunsaturated phospholipid.

애플리케이션

18:0-18:2 PS or 1-stearoyl-2-linoleoyl-sn-glycero-3-phospho-L-serine has been used in the preparation of liposomes. It might be used as a standard for the analysis of glycerophospholipid metabolism after exposure to polychlorinated biphenyl (PCB)-153 in PC12 cells through targeted lipidomics by ultra-high-performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) method.

포장

5 mL Clear Glass Sealed Ampule (840063P-10mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


시험 성적서(COA)

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문서 라이브러리 방문

Marco M Manni et al.
eLife, 7 (2018-03-16)
Phospholipid membranes form cellular barriers but need to be flexible enough to divide by fission. Phospholipids generally contain a saturated fatty acid (FA) at position sn1 whereas the sn2-FA is saturated, monounsaturated or polyunsaturated. Our understanding of the impact of
Warren G Hill et al.
American journal of physiology. Cell physiology, 289(1), C33-C41 (2005-02-25)
Caveolae are invaginated membrane structures with high levels of cholesterol, sphingomyelin, and caveolin protein that are predicted to exist as liquid-ordered domains with low water permeability. We isolated a caveolae-enriched membrane fraction without detergents from rat lung and characterized its
Anik Forest et al.
Journal of proteome research, 17(11), 3657-3670 (2018-09-27)
The goal of this work was to develop a label-free, comprehensive, and reproducible high-resolution liquid chromatography-mass spectrometry (LC-MS)-based untargeted lipidomic workflow using a single instrument, which could be applied to biomarker discovery in both basic and clinical studies. For this
Peter A Leventis et al.
Annual review of biophysics, 39, 407-427 (2010-03-03)
Phosphatidylserine (PS) is the most abundant negatively charged phospholipid in eukaryotic membranes. PS directs the binding of proteins that bear C2 or gamma-carboxyglutamic domains and contributes to the electrostatic association of polycationic ligands with cellular membranes. Rather than being evenly

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