810189P

TopFluor^™ PI(3,4,5)P3

Avanti Research^™ - A Croda Brand 810189P, powder

• 동의어(들): 1-oleoyl-2-{12-[4-(dipyrrometheneboron difluoride)butanoyl]amino}dodecanoyl-sn-glycero-3-phosphoinositol-3,4,5-trisphosphate (ammonium salt)
• 실험식(Hill 표기법): C₅₆H₁₀₈ BF₂ N₇O₂₃P₄
• CAS Number: 2260795-37-5
• Molecular Weight: 1420.19
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 분석: >99% (TLC)
• 형태: powder
• 포장: pkg of 1 × 50 μg (with stopper and crimp cap (810189P-50ug))
• 제조업체/상표: Avanti Research^™ - A Croda Brand 810189P
• 배송 상태: dry ice
• 저장 온도: −20°C

설명

일반 설명

PI(3,4,5)P3 (diacylphosphatidylinositol-3,4,5-trisphosphate) is restricted to the cell membrane of inner leaflet. TopFluor^™ PI(3,4,5)P3 is a fluorescently labeled-phosphoinositide derivative containing saturated acyl chain.

Phosphatidylinositol-3,4,5-trisphosphate (PI(3,4,5)P3) is an inadequate phospholipid present on the inner leaflet of the plasma membrane.

생화학적/생리학적 작용

PI(3,4,5)P3 (diacylphosphatidylinositol-3,4,5-trisphosphate) serves as a substrate for PTEN (phosphatase and tensin homolog), a tumor suppressor protein. It has binding affinity towards the active site of phosphatase domain. TopFluor^™ PI(3,4,5)P3 might be useful in monitoring protein induced phosphoinositide clustering. This product is considered photostable than other fluorophores.

Phosphatidylinositol-3,4,5-trisphosphate (PI(3,4,5)P3) plays a key role in inducing the cluster of Syntaxin1A at presynaptic terminals. It also regulates the activity protein kinase B/Akt.

포장

2 mL Amber Serum Vial with Stopper and Crimp Cap (810189P-50ug)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

TopFluor is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable