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Merck
모든 사진(2)

문서

810172P

Avanti

14:0-12:0 NBD PA

Avanti Research - A Croda Brand 810172P, powder

동의어(들):

1-myristoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphate (ammonium salt)

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About This Item

실험식(Hill 표기법):
C35H62N5O11P
CAS Number:
Molecular Weight:
759.87
UNSPSC 코드:
12352211
NACRES:
NA.25

분석

>99% (TLC)

형태

powder

포장

pkg of 1 × 1 mg (810172P-1mg)

제조업체/상표

Avanti Research - A Croda Brand 810172P

배송 상태

dry ice

저장 온도

−20°C

일반 설명

Phosphatidic acid (PA) is an anionic phospholipid with a phosphomonoester polar head group and two long hydrophobic acyl chains. It constitutes 1-4% of membrane lipids. NBD PA possess fluorescence analog, 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) at sn-2 fatty acid of PA.

생화학적/생리학적 작용

Phosphatidic acid (PA) serves as a parent compound to generate other phospholipids. It is a major signaling molecule in the regulation of cellular processes including cell proliferation, secretion and reproduction, cytoskeletal organization, and many more.

포장

5 mL Amber Glass Screw Cap Vial (810172P-1mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


시험 성적서(COA)

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문서 라이브러리 방문

Phosphatidic acid in membrane rearrangements
Zhukovsky MA, et al.
Febs Letters, 593(17), 2428-2451 (2019)
Mikhail A Zhukovsky et al.
FEBS letters, 593(17), 2428-2451 (2019-08-01)
Phosphatidic acid (PA) is the simplest cellular glycerophospholipid characterized by unique biophysical properties: a small headgroup; negative charge; and a phosphomonoester group. Upon interaction with lysine or arginine, PA charge increases from -1 to -2 and this change stabilizes protein-lipid
A Chauhan et al.
Neurochemical research, 25(3), 423-429 (2000-04-13)
Fibrillar amyloid beta-protein (Abeta) is the major protein of amyloid plaques in the brains of patients with Alzheimer's disease (AD). The mechanism by which normally produced soluble Abeta gets fibrillized in AD is not clear. We studied the effect of
Karen M Henkels et al.
Oncotarget, 7(30), 47002-47017 (2016-06-04)
The intracellular concentration of the mitogen phosphatidic acid (PA) must be maintained at low levels until the need arises for cell proliferation. How temporal and spatial trafficking of PA affects its target proteins in the different cellular compartments is not

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