QBD10631

Bis-MAL-Lysine-dPEG^®₄-TFP ester

• 동의어(들): Polyethylene glycol
• 실험식(Hill 표기법): C₃₇H₄₅F₄N₅O₁₃
• Molecular Weight: 843.77
• MDL number: MFCD28385461
• UNSPSC 코드: 12352108
• PubChem Substance ID: 329823944
• NACRES: NA.22

속성

• 분석: >90%
• 형태: solid or viscous liquid
• 반응 적합성: reagent type: cross-linking reagent; reactivity: thiol reactive
• 폴리머 구조: shape: linear; functionality: monofunctional
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: O=C(C(NC(CCN1C(C=CC1=O)=O)=O)CCCCNC(CCN2C(C=CC2=O)=O)=O)NCCOCCOCCOCCOCCC(OC3=C(C(F)=CC(F)=C3F)F)=O

설명

특징 및 장점

Bis-MAL-Lysine-dPEG^®₄-TFP ester is a unique crosslinker containing two maleimide groups, one on each amine of lysine, a 4-unit, single molecular weight dPEG^® spacer arm, and a 2,3,5,6-tetrafluorophenyl (TFP) ester. Each maleimide group reacts with a sulfhydryl group, and the TFP ester reacts with a free amine. The single molecular weight dPEG^® spacer is hydrophilic and non-immunogenic. This reagent can be used to modify or form conjugates with antibodies, antibody fragments, peptides, and small molecules.

법적 정보

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable