P8533

Tributylammonium pyrophosphate

• 동의어(들): N,N-dibutyl-1-butanamine diphosphate
• CAS Number: 5975-18-8
• MDL number: MFCD00136019
• UNSPSC 코드: 12352116
• PubChem Substance ID: 329820329
• NACRES: NA.22

속성

• 형태: powder
• 저장 온도: −20°C
• SMILES string: OP(O)(=O)OP(O)(O)=O.CCCCN(CCCC)CCCC.CCCCN(CCCC)CCCC
• InChI: 1S/2C12H27N.H4O7P2/c2*1-4-7-10-13(11-8-5-2)12-9-6-3;1-8(2,3)7-9(4,5)6/h2*4-12H2,1-3H3;(H2,1,2,3)(H2,4,5,6)
• InChI key: WRMXOVHLRUVREB-UHFFFAOYSA-N

설명

일반 설명

Tributylammonium pyrophosphate is a phosphorylating reagent used in the synthesis of modified dNTPs (deoxynucleoside triphosphates) which are important building blocks for the generation of DNA, RNA, functionalized nucleic acids.

애플리케이션

Reactant for:

• Enzymic synthesis of 3′-deoxy-apio-nucleic acid duplexes
• Synthesis of deoxynucleoside S-methylphosphonic acids
• Preparation of fluorescent non-nucleotide ATP analog N-methylanthraniloylamideethyl triphosphate

Tributylammonium pyrophosphate used as a phosphorylating reagent:

• In the synthesis of S′-deoxy-S′-methylphosphonic acid diphosphate along with 1, 1′-carbonyl diimidazole.
• In the synthesis of gram-scale level base-modified ribonucleoside-5′-O-triphosphates.
• In one-pot chemical synthesis of 2′-deoxynucleoside-5′-triphosphates with better protection.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)