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Merck
모든 사진(1)

Key Documents

CDE-509

Sigma-Aldrich

Diether Liposomes

14:0 Diether PC:Cholesterol (70:30 molar ratio 1mM)

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About This Item

UNSPSC 코드:
12352211
NACRES:
NA.25

Quality Level

구성

Phosphate buffered saline

농도

1 mM

불순물

30 mol % Cholesterol
70 mol % 14:0 Diether PC

입자 크기

100 nm

pH

7.4

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일반 설명

Liposomes are extensively used to study the interaction of proteins, peptides and other molecules with the surface of a lipid membrane. Ether lipids are a unique class of glycerophospholipids that have an alkyl chain attached to the sn-1 position by an ether bond.

Due to distinctive properties of ether lipids, liposomes made from ether lipids exhibit very unique characters and performance:
*ether bonds are more stable than ester linkages over a wide range of acidic or alkaline pH
*stability properties of the liposomes are enhanced by biopolar lipids and the saturated alkyl chains gives stability towards degradation in oxidative conditions
*the unusual stereochemistry of the glycerol backbone enhances the resistance against phopholipases

Due to their increased stability properties, ether liposomes are suitable candates for experiments that require an extended period of time as they can neither be hydrolyzed, oxidized, and can withstand higher temperatures.

애플리케이션

Drug delivery
Lipid-protein interactions

저장 및 안정성

Liposomes should never be frozen. Liposomes should be stored in the dark at 4°C, except when brought to room temperature for brief periods prior to use.

Liposomes are made under sterile conditions. If you need to take multiple aliquots out of the vial, it is advised to take extreme care in not contaminating the vial. It is recommended to handle the vial under a sterile hood to maintain the sterility of the product. Liposomes should never be frozen. Ice crystals that form during freezing will rupture the lipid membrane of the liposomes and change the size of liposomes particles.

법적 정보

Cellsome is a trademark of Encapsula NanoSciences
Product of Encapsula Nanosciences

면책조항

For research use only

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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